Bacteriological Profile and C Reactive Protein Level of Neonatal Septicemia
Journal Title: Journal of Medical Science And clinical Research - Year 2015, Vol 3, Issue 7
Abstract
Neonatal Sepsis is a life threatening emergency, and any delay in the treatment may cause death. Because of the importance of this problem, the objective of the present study was to determine the etiological agents and C Reactive protein level of neonatal septicemia. Two seventy three consecutive neonates with risk factors and clinical features suggestive of sepsis were selected as per operational definition and fulfilling the inclusion and exclusion criteria. Detailed physical examination was carried out. Blood samples for culture and CRP were taken from all the patients. Results of blood culture and CRP were noted down in the Performa. Culture positivity rate was 33%. Comparing with culture positivity, sensitivity of CRP was 67% and specificity was 60% in diagnosis of neonatal septicemia. Gram negative organisms constituted 64% of the total bacterial isolates. Klebsiella pneumoniae(40%) was the most common organism in early and late onset septicemia. This was followed by Staphylococcus aureus (19%), CONS (13%), Escherichia coli (10%), Enterobacter spp (7%), Pseudomonas aeuriginosa (5%), Aceinetobacter (2%) and streptococci (2%). Escherichia coli and streptococci were more prevalent in early onset septicemia than late onset septicemia. Single CRP level measured at the onset of infection lacks sufficient sensitivity to be useful in identifying neonate with septicemia. To reduce neonatal mortality due to infections, we must expand the research activities on diagnosis, etiology, and optimal management of neonatal sepsis at all levels of the healthcare system
Authors and Affiliations
Dr. B. Subitha
Keywords
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