Basaloid Squamous Cell Carcinoma of Tongue: A Report with Emphasis on Immunohistochemistry

Journal Title: Journal of Clinical and Diagnostic Research - Year 2017, Vol 11, Issue 3

Abstract

Basaloid Squamous Cell Carcinoma (BScc) is a rare entity with its histopathological distinction from conventional squamous cell carcinoma. It is frequently considered a high-grade carcinoma with poor prognosis because of higher rate of distant metastases. Here by, we are reporting a case of 39-year-old male with an ulcer on the left lateral border of the tongue since a month. Histopathological examination of incisional biopsy revealed basaloid tumour cell islands accompanied by component of well differentiated squamous cell carcinoma. To reconfirm this incidental finding immunohistochemistry was carried out for Proliferative Cell Nuclear Antigen (PCNA) and pancytokeratin (AE1/AE3) which was positive to conclude diagnosis of BScc. Further p16 staining was done to rule out Human Papilloma Virus (HPV) infection.

Authors and Affiliations

Karuna Kumari, Vanishree C Haragannavar, K Vineeth kumar, KAVITHA PRASAD, Shwetha Nambiar

Keywords

Related Articles

Surface Electromyographic Activity of Shoulder Muscles among People with Type 2 Diabetes- A Case-control Study

ABSTRACT Introduction: Increased prevalence of shoulder dysfunction among people with diabetes is a recognised source of disability resulting in functional impairments. Metabolic perturbations in diabetes result in glyco...

Diagnostic and Prognostic Significance of Ki-67 Immunohistochemical Expression in Surface Epithelial Ovarian Carcinoma

Introduction: The Surface Epithelial Ovarian Carcinoma (SEOC) at the moment of diagnosis, the disease is extended beyond the structures of the pelvis. Ki-67 is one of the prognostic marker which determines the growth fra...

Comparison of Pulmonary Function in Children with Cerebral Palsy and Normally Developed Children

ABSTRACT Introduction: Cerebral Palsy is one of the most common neurological disorders in children. It is characterised by varying degrees of disability affecting multiple domains. Respiratory complications, especially i...

Receiver Operator Characteristics (ROC) Analyses of Complete Blood Count (CBC) Delta

ABSTRACT Introduction: Delta check is a quality control tool that involves comparison of lab test result of current sample with that of previous sample from the same patient based on specified criteria. Though chemical a...

Randomised Control Study of Palonosetron Versus Dexamethasone in Preventing Postoperative Nausea and Vomiting Following Ear and Nose Surgeries under General Anesthesia

ABSTRACT Introduction: Postoperative Nausea and Vomiting (PONV) is defined as any nausea or vomiting that occurs during the first 48 hours after surgery. It is considered as a distressing event following anaesthesia. The...

Download PDF file
  • EP ID EP336848
  • DOI 10.7860/JCDR/2017/24308.9539
  • Views 141
  • Downloads 0

How To Cite

Karuna Kumari, Vanishree C Haragannavar, K Vineeth kumar, KAVITHA PRASAD, Shwetha Nambiar (2017). Basaloid Squamous Cell Carcinoma of Tongue: A Report with Emphasis on Immunohistochemistry. Journal of Clinical and Diagnostic Research, 11(3), 16-18. https://www.europub.co.uk/articles/-A-336848