Bell’s Palsy Treatment: Comparison of Famciclovir plus Prednisolone with Prednisolone Alone
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2018, Vol 6, Issue 4
Abstract
Not many Indian studies have evaluated role of antiviral drug Famciclovir in treatment of Bell’s palsy. Aim of this study was to analyze and compare clinical and electrophysiological recovery with Famciclovir plus prednisolone and prednisolone alone in treatment of Bell’s palsy. 50 patients with clinical features compatible with Bell’s palsy were included in the study .Detailed clinical, laboratory and electrophysiological evaluations of patients were done and patients were randomized into two groups. Group I received Famciclovir plus prednisolone while the Group II received 10 days of oral prednisolone alone. Outcome was assessed at 3 months with House–Brackmann scale and the patients were followed up to a period of three months. The mean age of patients was 35.0 years with M: F ratio of 64: 36. No significant differences exist between the groups in terms of age and gender. The rate of complete recovery was 68% in group I and 60% in the group II (p=0.04). The results of this study showed that the combined prednisolone and famciclovir therapy of patients with Bell’s palsy is more effective than treatment with prednisolone alone.
Authors and Affiliations
Dhermendra Pratap Singh, Sandeep Aggarwal, Kameshwar Prasad
Keywords
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