BILATERAL INTERNUCLEAR OPHTHALMOPLEGIA AS FIRST MANIFESTATION OF EXTRA PONTINE MYELINOLYSIS
Journal Title: International Journal of Medical Research & Health Sciences (IJMRHS) - Year 2014, Vol 3, Issue 3
Abstract
Extrapontine myelinolysis (EPM) is a rare clinical entity affecting anterior basal ganglia. This is one of the osmotic demyelination syndromes. It occurs due to rapid correction of hyponatremia and also rarely occurs in alcoholics. It generally presents with extrapyramidal symptoms. We here report a case of EPM in a 13 year old boy presenting with bilateral internuclear ophthalmoplegia and ptosis. The patient also had generalised weakness, but no psychiatric symptoms. The patient slowly recovered over six months. EPM can affect any age group, although the elderly are more likely to be affected due to frequent electrolyte abnormalities. Ocular movement disorders or brainstem signs are rarely reported in EPM. When present, it can create diagnostic confusion with multiple sclerosis. We believe this is the first report of this entity from India. The relevant literature regarding brainstem manifestations in myelinolysis syndromes is also discussed, along with the radiological findings.
Authors and Affiliations
Tushar Kanti Bandyopadhyay| Assistant Professor, Department of Medicine, Medical College Kolkata88, College Street, Kolkata, West Bengal, Rudrajit Paul| Assistant Professor, Department of Medicine, Medical College Kolkata88, College Street, Kolkata, West Bengal, Amit K Das| Resident, Department of Medicine, Medical College Kolkata88, College Street, Kolkata, West Bengal, Corresponding author email: docr89@gmail.com, Rathindranath Sarkar| Professor, Department of Medicine, Medical College Kolkata88, College Street, Kolkata, West Bengal
Keywords
Related Articles
- EP ID EP11245
- DOI 10.5958/2319-5886.2014.00428.7
- Views 282
- Downloads 11
Effective risk factors in Development of multiple sclerosis disease in Kermanshah
Background and purpose: Multiple sclerosis (MS) is a common Inflammatory demyelinating disease in central nervous system. So many genetically and environmental factors are involved in forming it. This study has been don...
Novel Electron Spin Resonance-Enzyme Immunosorbent Assay for Detecting Occult Hepatitis B Infection in HCV Chronic Liver Disease
Background: Hepatitis B virus infection in patients who lack detectable hepatitis B surface antigen (HBsAg) is called occult hepatitis B infection (OHB). The very low level of HBV genome may hamper its detection by mole...
Te Relation Between Laparoscopic Sleeve Gastrectomy and Ghrelin
Recently, obesity has become an important worldwide health problem. One of the obesity treatment alternatives is bariatric surgery methods and their effciency is increasing from day to day. In laparoscopic Sleeve gastre...
The effect of an Educative Intervention about Blood Pressure Control on levels of Knowledge and Self Efficacy in Patients Undergoing Hemodialysis: A Randomized Clinical Trial
Statistics show that hypertension is a common co-morbidity amongst hemodialysis patients. Knowledge and selfefficacy levels of the patient can affect health-related behaviors in managing the disease as well as the conseq...
EFFECT OF AMLODIPINE AND INDOMETHACIN IN ELECTRICAL AND PICROTOXIN INDUCED CONVULSIONS IN MICE
Background and Objectives: Antiepileptic drugs (AEDs) are the drugs used in the treatment of epilepsy. Many AEDs have been developed, but the ideal AED which can not only prevent but also abolish seizures by correcting...