Bile culture and sensitivity in post cholecystectomy specimens
Journal Title: Medpulse International Journal of Surgery - Year 2017, Vol 3, Issue 1
Abstract
Background: Without previous biliary intervention, most bile is considered sterile. However, with the presence of stones or obstruction, the likelihood of bacterial contamination increases. With nucleation of bile and gallstone formation, gallstones can provide a reservoir for bacteria, but the source of the bacteria is unclear. In that most bactobilia is caused by gram-negative aerobes, passage of bacteria upward from the duodenum into the biliary tree is a commonly held explanation for bacterial contamination. The most common types of bacteria found in biliary infections are Enterobacteriacae, such as Escherichia coli, Klebsiella, and Enterobacter, followed by Enterococcus spp. To cover the most common bacterial species, a first- or second-generation cephalosporin or fluoroquinolone should suffice. For those undergoing elective laparoscopic cholecystectomy for biliary colic, no antibiotic prophylaxis is necessary. However, antibiotics should be used for any patient with suspected or documented infection of the biliary tree, such as acute cholecystitis or ascending cholangitis, and should be chosen to cover gram-negative bacteria and anaerobes. Methodology: In this study we have collected bile aspiration samples from cholecystectomy specimens from 2 years from January 2015 to January 2017 and tabulated the organisms and culture sensitivity in Yenepoya medical College, Mangalore. Results: Among 76 patients, 52 bile culture was sterile. E.coli (6) and Klebsiella (4). The organisms were sensitive to Colistin (26.3%) and Imipenem (23.7%) accordingly. And a resistence for Amikacin and Gentamycin was noted as per the study conducted in Yenepoya University, Mangalore.
Authors and Affiliations
Abhijith Sudhakar Shetty, Sonali Prabhakar, Moosabba M S
Keywords
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