Biliary Dysfunction in Children with Iron Deficiency
Journal Title: Здоров`я дитини - Year 2016, Vol 3, Issue 71
Abstract
Background. Functional disorders of the biliary tract (FDBT) remain a topical problem of pediatric gastroenterology due to the high incidence and progressive course with formation of chronic cholecystitis and cholelithiasis in patients. Iron deficiency (ID) has a well-known effect on the course of the gastrointestinal tract pathology. With the aim of evaluating the state of the biliary system and clinical features of FDBT associated with ID, a case-control study was conducted in 160 children aged 9 to 17 years, who underwent in-patient treatment for exacerbation of biliary tract pathology. According to the iron metabolism tests, children were divided into 3 groups: I — 29 children with FDBT and I degree anemia; II — 91 children with FDBT and latent ID; III — 40 children with FDBT and normal iron metabolism parameters. Research methods included: the study of anamnesis, clinical examination, complete blood count, serum iron level, total iron-binding capacity, calculation of percent transferrin saturation, ultrasound of the abdominal organs and dynamic ultrasound cholecystography with choleretic breakfast. Results. The study found that children with FDBT and ID have a higher incidence of FDBT exacerbations, increased intensity of dyspeptic and asthenovegetative symptoms in case of FDBT exacerbation, increase in size, reduced contractile function of gallbladder (GB) and hypotonic-hypokinetic FDBT type. Conclusions. Children with FDBT and ID have burdened course of FDBT due to the high incidence of exacerbations, severe dyspeptic and asthenovegetative symptoms in the acute phase, as well as reduced contractile function of GB and hypotonic-hypokinetic FDBT type, which is clinically unfavorable because of the risk of biliary sludge and cholelithiasis.
Authors and Affiliations
Yu. V. Marushko, K. I. Nagorna
Keywords
Related Articles
- EP ID EP191996
- DOI -
- Views 110
- Downloads 0
Interferons: the Nature, Mechanisms of Action and Clinical Use of Interferon Preparations
The lecture deals with the use of interferons in the clinical practice. Attention is paid to the history of the discovery of interferons, mechanism of their action, efficacy of various interferon preparations.
Prediction of the severe course of bronchial asthma in children
Background. Bronchial asthma (BA) is a chronic heterogeneous respiratory disease in children, 339 million people in the world suffer from it. Severe course of BA is characterized by difficulties in disease control and r...
Bactericidal Activity of Probiotic Agents
The article grounds the symbiotic drugs tp inhibit the growth of pathogenic flora, to improve immune status, to enhance the general resistance of the organism to the pathogenic contagions.
Runny Nose in Children
The article noted the importance and prevalence of acute rhinitis in children associated with a runny nose and difficulty in nasal breathing. A method for safe and effective treatment of rhinitis in children — irrigation...
Primary Hemophagocytic Lymphohistiocytosis in an Infant
The paper considers the results of a clinical observation of an infant with hemophagocytic lymphohistiocytosis complicated with spontaneous splenic rupture. There were discussed the questions on diagnosis according to Hi...