Bioactive Compounds from Medicinal Plants and Their Importance in Drug Discovery in Pakistan

Journal Title: Matrix Science Pharma (MSP) - Year 2017, Vol 1, Issue 1

Abstract

Humans have relied on nature throughout their ages to cater for their basic needs including medicines to cure a wide spectrum of diseases. Plants have formed the basis for sophisticated systems of traditional medicines. For therapeutic agents many of the presently known lead compounds are natural products or their derivatives. Ethnomedicinal studies play a vital role to discover new drugs from indigenous medicinal plants. Green pharmaceuticals are getting popularity and extraordinary importance because vast opportunities for new drug discoveries are provided by the unmatched availability of chemical diversity and natural products either as pure compounds or as homogenous plant extracts. Therefore, in recent years the demand for herbal medicines and several natural products from a variety of plant species is consistently increasing. In spite of being an agricultural country and having different ecological regions, the medicinal plants of Pakistan have not been explored for their secondary metabolites which are responsible for treating different diseases. Although, huge importance of different extracts of medicinal plants from Pakistan have been reported for their different activities such as antimicrobial, anti-cancerouse, antiviral and antioxidant but complete biochemical profiling of these medicinal plants is lacking. LC-MS and GC-MS techniques have been applied in the field of drug discovery from medicinal plants but in Pakistan its success rate is very low in the subject of biochemical profiling. Therefore, such techniques should be used in Pakistan to explore active constituents from medicinal plants which could be used as medicines in future

Authors and Affiliations

Ghulam Mustafa, Rawaba Arif, Asia Atta, Sumaira Sharif, Amer Jamil

Keywords

Related Articles

EDITORIAL: PROBLEM BASED LEARNING: A WAY FORWARD FOR THE MODERN TIMES

Over the years teaching and learning has shifted from teacher centered towards student centered learning. Internet and smart tools in addition has provided a progressive user-friendly platform for learning and gaining kn...

TETANUS IN A SURGICALLY CASTRATED BEETAL BUCK: A CASE REPORT

Tetanus is a fetal disease of human and animals caused by spore forming, Gram-positive, anaerobic bacterium Clostridium tetani. In present report, a 16-month old, Beetal buck, weighing about 40 kg was presented to outdoo...

PHARMACOKINETIC STUDY OF CLARITHROMYCIN IN HUMAN FEMALE OF PAKISTANI POPULATION

The study was designed to assess the various pharmacokinetic parameters of a commercially available clarithromycin Tablet (Klaricid® 250 mg Abbot, Pakistan) in plasma sample of healthy adult female volunteers by applying...

STATISTICAL ANALYSIS OF RISK FACTORS AFFECTING THE PROGNOSIS OF BILIARY ATRESIA IN INFANTS

Biliary atresia often neglected as normal transition neonatal jaundice reports high incidence in Pakistan in contrast to worldwide statistics. In contrast to data reported worldwide high mortality and morbidity rate of B...

PHYTOCHEMICAL AND ANTIOXIDANT SCREENING OF AMOMUM SUBULATUM, ELETTARIA CARDAMOMUM, EMBLICA OFFICINALIS, ROSA DAMASCENE, SANTALUM ALBUM AND VALERIANA OFFICINALIS AND THEIR EFFECT ON STOMACH, LIVER AND HEART

Plants and herbs are the mainstream of diverse traditional medicine system practiced throughout the whole population. Today, there is increasingly trend set the uses of natural plants for the various human ailments and w...

Download PDF file
  • EP ID EP264152
  • DOI 10.26480/msp.01.2017.17.26
  • Views 161
  • Downloads 0

How To Cite

Ghulam Mustafa, Rawaba Arif, Asia Atta, Sumaira Sharif, Amer Jamil (2017). Bioactive Compounds from Medicinal Plants and Their Importance in Drug Discovery in Pakistan. Matrix Science Pharma (MSP), 1(1), 17-16. https://www.europub.co.uk/articles/-A-264152