Biochemical Evaluation of Trigonella Foenum-Graecum Seed Extract in Metabolic Syndrome
Journal Title: Galore International Journal of Health Sciences and Research - Year 2018, Vol 3, Issue 3
Abstract
Background: Metabolic syndrome is a crucial factor in causation of type 2 diabetes mellitus (T2DM) and coronary heart disease (CHD). Fenugreek seeds have beneficial effects on improvement of metabolic syndrome. Objective: Evaluation preventive and curative efficacy of aqueous extract of fenugreek seeds in metabolic syndrome by observation of biochemical parameters and its correlation. Methods: Case control study consisting of controls (n=34) and subjects (n=34) with metabolic syndrome. Case group was administered aqueous extract of fenugreek seeds equivalent to 13.2gm powder/day for 3 months. Both groups were evaluated at base line and after three months while status quo was maintained. Subjects were advised not to alter their lifestyle. Results: After three months of adjunct therapy, there was significantly improvement in glycaemic status, insulin resistance, HOMA, and antioxidant superoxide dismutase (SOD) in metabolic syndrome when compared with control group. Conclusion: Aqueous extract of fenugreek seeds is effective and safe to control glycaemic, insulin resistance, dyslipidaemias and antioxidant status in metabolic syndrome.
Authors and Affiliations
Mrinalini S. Patwardhan
Keywords
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