BIOCHEMICAL STUDIES ON GALECTIN-3 AS FIBROTIC MARKER IN HEPATITIS C PATIENTS
Journal Title: WORLD JOURNAL PHARMACY AND PHARMACEUTICAL SCIENCE - Year 2018, Vol 7, Issue 3
Abstract
Although it is the gold standard for assessing hepatitis C virus (HCV)-related fibrosis, Liver biopsy is invasive and prone to complications. This study was designed to study non-invasive methods for the assessment of liver fibrosis where hepatitis C virus (HCV) is common in Egypt. Our aim was to validate and compare the performance of GAL-3 as simple blood marker for different stages of liver fibrosis in HCV patients in addition to GSH and NO. The study was carried out on 90 individuals divided into the following groups: group 1: normal control, group 2: F1 = portal fibrosis without septa, group 3: F2 = few septa, group 4: F3 = numerous septa without cirrhosis and group 5: F4= cirrhosis. Our results showed a positive correlation between GAL-3 level and degree of liver fibrosis. We can concluded that, using of GAL-3 a simple and non-invasive biochemical markers for the assessment of different stages of hepatic fibrosis as alternative to liver biopsy
Authors and Affiliations
Dina Mohamed Mohamed
Keywords
Related Articles
- EP ID EP622146
- DOI -
- Views 144
- Downloads 0
“LAVANADI VARG-AN AYURVEDIC ASPECT AS WELL AS MODERN ASPECT”
In Ayurveda Pharmaceutics broad spectrum of dosage forms is mentioned. In it Lavana Kalpas is one where lavana (salt) is the main ingredient in the formulation. It is prepared by Combining lavana along with different her...
APPLICATION OF GC-MS IN DETERMINATION OF MALATHION IN ENVIRONMENTAL SAMPLES.
A sensitive gas chromatography mass spectrometry (GC-MS) method was developed for determination of malathion in water samples. In this study, determination of malathion has been carried out according to standard method f...
SILVER NANOPARTICLES FUNCTIONALIZED GEL: PHYSICO-CHEMICAL PROPERTIES AND ANTIBACTERIAL ACTIVITY AGAINST ESCHERICHIA COLI, PSEUDOMONAS AERUGINOSA AND STAPHYLOCOCCUS AUREUS
This study was performed to verify the stability, physicochemical properties and antibacterial activity of a carbomer based gel functionalized with silver nanoparticles (AgNPs) obtained by green synthesis. Three formulat...
SHATAVARI (ASPARAGUS RACEMOSUS) A AYURVEDIC DRUG REVIEW
Ayurveda is an ancient and the oldest medical system in the world. Dating back almost 5000 years, it is also considered to be an ancient science of healing that enhances longevity. Herbal medicines are considered to be s...
NANOTECHNOLOGY AND ITS IMPLEMENTATIONS IN VARIOUS DISEASE STATES: A COMPREHENSIVE REVIEW
With the progression of time and science, disease curability has increased, but so has the emergence of new diseases. Autoimmune diseases are the latest enemy of mankind in the path to a long and healthy life. Diseases l...