Bone Marrow Studies in Geriatric Anaemic Patients
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2018, Vol 3, Issue 2
Abstract
Purpose: To evaluate Bone marrow studies in anaemic geriatric patients. Methods: Bone marrow in 75 cases of anaemia in elderly >65yrs as defined by the WHO were studied in 24 months. Clinical History, Biochemical, Radiological investigations, Haematological parameters using LH750 and Peripheral blood smears were recorded and correlated. These anaemias were classified etiologically and morphologically in correlation with their bone marrow findings Results: Bone marrow studies in 75 cases of anaemic elderly were studied. There were 14 cases of Multiple Myeloma, 9 cases of haemophagocytosis, 8 cases of reactive marrow, 7 cases of megaloblastic anaemia and 6 cases of aplastic anaemia, 5 cases of Immune thrombocytopenia purpura(ITP), 5 cases of Lymphoproliferative disorder ( LPD), 3 cases each of Acute myeloid leukemia (AML),Iron deficiency anaemia(IDA), hypocellular marrow , Myelodysplastic syndromes ( MDS) and infectious etiology respectively. There were 2 cases of hypersplenism and 1 case each of myelofibrosis, metastasis from prostatic adenocarcinoma, eosinophilia and Chronic myeloid leukemia (CML) respectively. These findings were correlated with the etiological and morphological classification of these anaemias. Conclusions: The two most common enitities on bone marrow examination in our study were Multiple Myeloma followed by haemophagocytosis. These were more often anaemias due to chronic diseases (etiological classification) and normocytic normochromic anaemias (morphological classification). Bone marrow was found to be an essential requirement of the workup of elderly patients with anaemias in view of the variety of findings and unexplained cytopenias seen in geriatric age group.
Authors and Affiliations
Amit Nisal
Keywords
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