Brachial plexus block using lidocaine/ epinephrine or lidocaine/ xylazine in fat-tailed sheep

Journal Title: Veterinary Research Forum - Year 2013, Vol 4, Issue 3

Abstract

This blinded, randomized experimental study was designed to evaluate the analgesic effects of adding epinephrine or xylazine to lidocaine solution for brachial plexus block (BPB) in sheep. Nine healthy, fat-tailed female lambs (26.6 ± 1.5 kg) were randomly allocated into three groups: lidocaine 2%, 5 mg kg-1 (LID, n = 6), lidocaine (5 mg kg-1) with epinephrine 5 µg mL-1 (LIDEP, n = 6) or lidocaine (5 mg kg-1) with xylazine 0.05 mg kg-1 (LIDXY, n = 6). Each animal was tested twice. The sheep received a total volume of 0.25 mL kg-1 for BPB. A nerve stimulator was used to locate the nerves of the brachial plexus. Onset and duration of analgesia of the forelimb were evaluated using superficial and deep pin prick and pinching of skin with a hemostat clamp. Heart and respiratory rates, and rectal temperature were recorded before and at predetermined intervals following the completion of the block. Brachial administration of LID, LIDEP or LIDXY produced forelimb analgesia within 11.3, 11.0 and 7.0 minutes, respectively. The mean duration of analgesia was 100.0 min in LID and 133.2 min in LIDEP group. The mean duration of analgesia in LIDXY group (186.8 min) was significantly longer compared with LID group. In LIDEP group a significant increase in heart rate occurred 5 min after drug administration. Heart rate decreased from 35 to 80 minin sheep received LIDXY. In conclusion, the addition of xylazine to lidocaine solution for BBP provided a prolonged duration of action without any adverse effects in fat-tailed sheep.

Authors and Affiliations

Safoura Ghadirian, Nasser Vesal

Keywords

Related Articles

 Luteal activity of Abadeh ecotype does in summer and winter and the effect of kisspeptin-10 on luteinizing hormone secretion in the anestrus does

 The aims of the present study were to evaluate luteal activity in Abadeh ecotype goat during summer and winter and also the effect of a single dose kisspeptin-10 injection on the secretion of luteinizing hormone (L...

Occurrence of congenital cerebral theileriosis in a newborn twin Holstein calves in Iran: Case report

An 8-day-old newborn female twin Holstein calves with a history of weakness, anorexia, emaciation and convulsion were presented to Tabriz University Veterinary Teaching Hospital. On admission, the calves were febrile and...

Effects of diluting medium and holding time on sperm motility analysis by CASA in ram

The aim of this study was to evaluate the effects of dilution rate and holding time on various motility parameters using computer-assisted sperm analysis (CASA). The semen samples were collected from three Ghezel rams. S...

Effects of flunixin meglumine on experimental tendon wound healing: A histopathological and mechanical study in rabbits

Tendons are frequently targets of injury in sports and work. Whether nonsteroidal anti-inflammatory drugs (NSAIDs) have beneficial effects on tendon healing is still a matter of debate. This study was conducted to evalua...

Detection of tetracycline resistance genes in bacteria isolated from fish farms using polymerase chain reaction

Five common tetracycline resistance genes tet(A), tet(B), tet(M), tet(O) and tet(S) were studied by polymerase chain reaction in 100 bacteria isolated from Iranian fish farms. In the antibiogram test most of the bacteria...

Download PDF file
  • EP ID EP87719
  • DOI -
  • Views 150
  • Downloads 0

How To Cite

Safoura Ghadirian, Nasser Vesal (2013). Brachial plexus block using lidocaine/ epinephrine or lidocaine/ xylazine in fat-tailed sheep. Veterinary Research Forum, 4(3), 161-167. https://www.europub.co.uk/articles/-A-87719