Breast sarcoma surgical management: a five-year multicentric study
Journal Title: Journal of Clinical and Investigative Surgery - Year 2016, Vol 1, Issue 2
Abstract
Background. Breast sarcomas are a heterogeneous group of breast neoplasms with a low incidence and a reserved prognosis. No treatment protocol has been yet established, a guideline similar to soft tissue sarcomas is used. Materials and Methods. Our study analyzed all the patients admitted with the diagnosis of malignant breast disease in two specialized centers on a five-year time frame. We compared long term results for the patients who underwent conservative treatment and mastectomy. Results. A total of 76 cases received surgical treatment with curative intent, 24 conservative procedures and 52 mastectomies. Incidence of local recurrence does not appear to be closely related to the type of surgical procedure. There were a number of five local recurrences for patients who received conservative treatment and 7 local recurrences where we used mastectomy. Kaplan-Meier analysis conducted shows no differences statistically significant (sig = 0.459) between the results of conservative treatment and mastectomy. Basically conservative surgery seems to get similar results, provided that R0 resection objective can be met. Conclusions. Treatment options are more limited for breast sarcomas than carcinomas, the role of surgery being more important to therapeutic success. The biological characteristic of the tumor including histological type and sub-type, play an important role in determining the results and the treatment should be tailored and adapted for each case.
Authors and Affiliations
Răzvan Scăunașu, Traean Burcoș, Ștefan Voiculescu, Cristina N. Cozma, Bogdan Popescu, Eugen Brătucu
Median sternotomy - gold standard incision for cardiac surgeons
Sternotomy is the gold standard incision for cardiac surgeons but it is also used in thoracic surgery especially for mediastinal, tracheal and main stem bronchus surgery. The surgical technique is well established and id...
Larynx stenosis; a challenge for the ENT surgeons
Laryngo-tracheal stenosis is a complex pathology which requires multiple surgical interventions and diligence from the surgeon and patience from the patient so that normal physiology may be restored. The aim of this pape...
A rare case of vulvar squamous cell carcinoma; case presentation
Objectives. Vulvar cancer is a rare gynecological malignancy, with an incidence of 1.5 per 100 000 women/year. The most common vulvar cancer is developed in squamous cells, the most encountered type of skin cells. Case r...
Platelet Rich Plasma- mechanism of action and clinical applications
Platelet-rich plasma (PRP) is a blood-derived fraction containing high level of platelets, a high concentration of leukocytes and growth factors. PRP therapy has been growing as a viable treatment alternative for a numbe...
Open versus arthroscopic surgery in acromioclavicular separation
Acromioclavicular separation is a very serious injury at the level of shoulder. Lesion of the acromioclavicular joint is a usual clinical condition because of its superficial situation. It is often involved in trauma of...