Cardiovascular Changes during Chronic Hypertensive States
Journal Title: Journal of Medical Science And clinical Research - Year 2016, Vol 4, Issue 8
Abstract
Hypertension is currently the single most important contributor to death around the world in both developed and developing regions. Elevated blood pressure is a major risk factor for coronary heart disease, atrial fibrillation, heart failure, cerebrovascular disease and peripheral artery disease. Hypertensive heart disease consists of both vascular and myocardial changes. Various mechanisms are responsible for hypertensive heart disease, including endothelial dysfunction and coronary arteriolar constriction causing ischemia of the myocardium, increased fibrosis, apoptosis and inflammatory changes. Studies also shown that major risk factors such as dyslipidemia and also diabetes stratifies the patient into high risk group. Hypertension induces a compensatory thickening of the ventricular wall in an attempt to normalize wall stress, which results in concentric LVH, which in turn decreases LV compliance and LV diastolic filling, causing heart failure. Enlargement of the left atrium results in stretching of the atrial fibers, causing arrythmias and increased blood flow causes damage and narrowing of arteries resulting in coronary artery disease.
Authors and Affiliations
T. A. Naufal Rizwan
Keywords
Related Articles
- EP ID EP214214
- DOI -
- Views 109
- Downloads 0
Laparoscopic Management of Hepatic Hydatid Cyst: A Case Report
Hydatid disease is quite prevalent in India; common in most of the states, of which Andhra Pradesh and Tamil Nadu predominate. Hydatid disease is mainly caused by infection of the tapeworm Echinococcus granulosus. We pre...
Evaluation of Homocysteine, hsCRP and Microalbuminuria in Hypertensives without and with end Organ Damage-A Case Control Study
Background: Homocysteine considered to be a marker of endothelial dysfunction is formed from a sulfurcontaining amino acid, methionine. The total plasma homocysteine levels are between 5-15 µmol / L in healthy individual...
To Study the Clinical Profile among Different Bethesda Categories of Thyroid Lesions: A Study of 917 Cases
Background: Fine needle aspiration (FNA) is the primary diagnostic tool in initial evaluation of the thyroid lesions. The New Bethesda System for Reporting Thyroid Cytopathology (TBSRTC) is considered a standard reportin...
Pharmacoeconomic Study of the Prescription Pattern of Psychotic Disorders in Psychiatry OPD
Aims and Objectives: 1) To study prescription patterns in psychiatry outpatient department in tertiary care teaching hospital. 2) To determine drug utilization pattern in psychiatry OPD. 3) To analyze cost of prescriptio...
Epidemiology of Paediatric Open Globe Injuries
Purpose: To study the epidemiology of the paediatric open globe injuries (OGI) at tertiary care centre in central India in detail, such a way, that to reduce the incidences of OGI with the help of detailed epidemiologica...