Cardiovascular Risk Status According To Lipids Levels In Type 2 Diabetic Patients
Journal Title: International Journal of Basic and Applied Physiology - Year 2013, Vol 2, Issue 1
Abstract
Background: Diabetes mellitus is a common secondary cause of hyperlipidaemia, particularly, if glycaemic control is poor, which in-turn is an important risk factor for atherosclerosis and coronary heart diseases. The aim of the study was to define dyslipidaemia pattern among type 2 diabetic patients using ATP (Adult treatment panel) III guidelines for the classification of lipoprotein concentrations into cardio vascular disease risk categories. Method: The present study was conducted on 100 type 2 diabetics males aged 40-60 years. Among them, 30patients having HbA1c levels ≤7 were categorized as having good glycaemic control (group-1), and 70 patients having HbA1c levels >7 were categorized as having poor glycaemic control (group-2). We assessed the percentage of patients falling into desirable, borderline and high risk categories according to the criteria laid down by ATP III guidelines. Result: Mean age (49.09 vs 50.5 years, P=0.13) and duration of diabetes (6.9 vs 8 years, P=0.07) was not different between the two groups. Compared to good glycaemic control group, diabetics with poor glycaemic control were significantly more in high cardiovascular risk status (P < 0.05) according total cholesterol levels. According to LDL-C levels and TG levels number of diabetics with poor glycaemic control were significantly higher in borderline cardiovascular risk status (P<0.01). Conclusion: We concluded that diabetic patients particularly those with poor glycaemic control are at high cardiovascular risk status according to serum cholesterol levels and borderline risk according to LDL-C levels and TG levels. Reductions in Trans and saturated fats are mainstays for reducing LDL-C. Reduced body weight (10%), more physical activity and improvement in glycaemic control more favourably modified TG, HDL-C and LDL-C.
Authors and Affiliations
Dinesh Parmar, Ashvin Sorani, Dr. Rajesh Kathrotia, Neeta Mehta
Keywords
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