Changes of refractive statues in infants with retinopathy of prematurity after different treatments
Journal Title: Eye Science (Yanke Xuebao) - Year 2022, Vol 37, Issue 10
Abstract
[Objective:] To observe the changes of refractive statues in infants with retinopathy of prematurity retinopathy of prematurity (ROP) after different treatments. [Methods:] According to different treatment methods, 72 cases (127 eyes) of infants with ROP were divided into 3 groups: laser photocoagulation group, intravitreal injection of anti-vascular endothelial growth factor (VEGF) drugs group and natural regression group. Their sphere and spherical equivalent were measured by retinoscopy optometrist after the ciliary muscles paralyzed. The data before treatments and 1, 4, 7 and 12 months after treatments were recorded and analyzed. [Results:] The differences of sphere and spherical equivalent among three groups were statistically significant: intravitreal injection of VEGF drugs group was lower than natural regression group and the laser photocoagulation group, but there was no significant difference between natural regression group and laser photocoagulation group. Incidence of myopia of laser photocoagulation, intravitreal injection of VEGF drugs, natural regression group were 2.4%, 7.8%, 2.0%, which was not statistically significant. [Conclusion:] There was no significant difference about the incidence rate of myopia among the three groups, but the emmetropization in infants with ROP after intravitreal injection of anti-VEGF drugs might be faster in the future.
Authors and Affiliations
Xue YIN, Hui YANG, Zheng FU, Xixiang WEI, Weiwei XIONG, Xiuting LI
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