CHANGING THE LIPID PROFILE AND RENAL FUNCTIONS BY ALLIUM SATIVUM, NIGELLA SATIVA AND HIBISCUS SABDARIFFA IN ESSENTIAL HYPERTENSIVE PATIENTS
Journal Title: WORLD JOURNAL PHARMACY AND PHARMACEUTICAL SCIENCE - Year 2018, Vol 7, Issue 5
Abstract
Background: Essential hypertension is a global major health problem affecting more than a billion individual. The aim of the present study is to find out a new effective agent with high safety and low cost by examining Allium sativum, Nigella sativa, and Hibiscus sabdariffa as compared with antihypertensive drug Ramipril. Materials and Methods: This study was conducted on 24 hypertensive patients by examining effects of these agents on systolic and diastolic blood pressure in addition to investigating changes in serum lipid profile (cholesterol, triglycerides [HDL and LDL]) and changes in renal functions (serum urea nitrogen, creatinine, uric acid, and electrolytes: Na+, K+, and Ca++) after administering these agents for 4 weeks. Results: There was a significant lowering effect of the four agents on both systolic and diastolic BP. Garlic has shown a significantly elevated HDL while roselle has shown a significantly decreased LDL levels. Other values of lipid are decreased. Moreover, a significant decrease in serum creatinine level with garlic and black seed is seen with a significant decrease of blood urea nitrogen level with roselle. The uric acid and sodium levels are significantly reduced with garlic. Conclusion: There is an advantageous effect of using these agents in hypertension therapy.
Authors and Affiliations
Dr. Zaid Al-Attar
Keywords
Related Articles
- EP ID EP626120
- DOI -
- Views 204
- Downloads 0
SYNTHESIS, STRUCTURAL CHARACTERIZATION AND ANTIBACTERIAL EVALUATION OF SOME NEW PYRROLIDINE DERIVATIVES
2-naphthyl chalcones where prepared by using Claisen-Schmidt condensation. In addition, Schiff bases were produced by condensation of benzyl amine with substituted benzaldehyde, adding the latter to the chalcones by 1,3-...
EXTRACTION AND PURIFICATION OF LOCALYHORSERADISH PEROXIDASE
Horseradish peroxidase is a comprising enzyme which canbe appropriate to oxidoreductases and is intricate indegradation of definiteintractable organic complexes like phenol and substituted phenol via freeradical polymeri...
SOLID WASTE MANAGEMENT: A CHALLENGE TO OUR SOCIETYCASE STUDY JHANSI, UTTAR PRADESH
The waste has potential to pose threat to land air and soil. The poor solid waste management leads to social, economic, health and environmental problems. Jhansi is famous for being tourist city of the UP state. The prob...
ROLE OF CLINICAL PHARMACISTS, INTERACTION WITH DOCTORS AND THE BARRIERS FACING THEM IN KHARTOUM STATE PUBLIC HOSPITALS, KHARTOUM, SUDAN, 2013
Clinical Pharmacy is the use of the pharmacist’s skills and knowledge of drugs and therapeutics to improve patient care (pharmaceutical care). Objectives To assess the role of clinical pharmacists (CPs), their interactio...
A REVIEW OF RICINUS COMMUNIS LINN.
Ricinus communis Linn. is a widely described plant since ancient time in Vedas, Puranas, Samhitas and Nighantus. It is generally used in diseases in neuro-muscular disorders like generalized pain, inflammation, hemiplegi...