Characteristics of multi drug resistant tuberculosis cases at a selected tertiary level hospital
Journal Title: International Journal of Medical Research and Review - Year 2017, Vol 5, Issue 1
Abstract
Background: This study was carried out to determine the characteristics of MDR-TB cases under treatment at National Institute of Diseases of the Chest and Hospital (NIDCH), Mohakhali, Dhaka. Methods: This was a descriptive cross sectional study among 442 diagnosed MDR-TB patients admitted in NIDCH of which 303 MDR-TB patients were included as respondents. The respondents were selected purposively and they were interviewed with duly pre-tested research instruments. Results: Among the study populations (303), all were resistant to H & R and 149 (57.7%) consumed standard drugs regimen contained H, R, E & S. In addition the factors related to develop MDR-TB mostly as non-compliance, overcrowding and exposure to MDR-TB were 190 (73.7%), 261 (86.1%) and 81 (26,7%) respectively. In this study, time interval between completed anti-TB treatment and diagnosis of MDR-TB found 01 to 06 years among 55.4% respondents. Moreover tools used for diagnosis of MDR-TB were found in 258 (85.1%) as smear for AFB, Gene expert tests and Culture. Age group 16 to 30 yrs 184 (60.7%), income group 10001 to 20000 taka per month 143 (47.2%), educational qualification class VI-X 72 (23.8%) and urban population 180 (59.4%) were affected more. The association between type of house, crowding status and occurrence of MDR-TB were found statistically significant (p<0.05) but source of drugs, compliance of treatment, availability of drugs and occurrence of MDR-TB shown statistically highly significant, (p<.001). Correlation with age, family income and time gap of diagnosis MDR-TB was statistically significant (p<0.05). Principal Conclusion: Study findings demands establishment of standard diagnostics procedures/laboratories at all secondary and tertiary care hospitals and TB clinics in the country in support of uniformity of intervention therapy.
Authors and Affiliations
A K Mahbubul Hoque, Mahfuzar Rahman, S. M. M. Saleh Bhuiyan, MD Mahbubur Rahman
Keywords
Related Articles
- EP ID EP265182
- DOI 10.17511/ijmrr. 2017.i01.10
- Views 151
- Downloads 0
Awareness of palliative care among general practioners of Bhopal: a cross sectional study
Introduction: Palliative medicine is one of the developing medical specialities. This study was undertaken to enquire about the level of awareness regarding various aspects of palliative care among general practitioners...
Diagnostic accuracy of pleural fluid adenosine deaminase in tubercular pleural effusion
Background: In India, tuberculosis is an endemic disease. Delay in diagnosis results in poor prognosis and fast spread of the disease. The objective of the present study is to look for an effective and acceptable diagnos...
Double Trouble: an observational study of thyroid dysfunction in South Indian subjects with type 2 diabetes
Objective: Studies conducted in subjects with type 2 diabetes have shown increased prevalence of overt hypothyroidism and subclinical hypothyroidism. Hence, we designed a study to find out the prevalence of thyroid dysfu...
Neonatal Kasabach-Merritt Syndrome (KMS): case report
A 2days baby girl presented with congenital reddish-blue swelling over chest and abdomen with thrombocytopenia. The clinical, imagining and laboratory findings suggested the diagnosis of KMS. Oral steroid was started wit...
Role of bacterial vaginosis in preterm labor - a prospective study
Objective: To study the incidence of bacterial vaginosis in pregnant women in preterm labor and in labor at term and the relation of bacterial vaginosis with preterm delivery, neonatal birth weight and puerperal sepsis....