Chronic comorbidity of internal organs as a risk factor of complications and fatal outcome of community-acquired pneumonia
Journal Title: Медичні перспективи - Year 2018, Vol 23, Issue 1
Abstract
With the purpose to estimate influence of comorbidity at the risk of complications and death due to community-acquired pneumonia (CAP) the retrospective analysis of 1587 case histories of inpatients with CAP (mean age – 48.5±18.4, males – 815 (51.4%), women – 772 (48,6%)) was performed. Comorbidity was observed in 1114 (70.2%). More frequently complications of CAP were developed in patients with chronic diseases than without them (p=0.013). Increased risk of pleural effusion was associated with chronic diseases of digestive system (OR=1.85 (95%CI 1.30-2.26)) and diabetes mellitus (OR=2.35 (95%CI 1.40-3.96)). Risk of sepsis development is higher in patients with nervous system diseases (OR=3.62 (95%CI 1.37-9.56) and drug or alcohol addiction (OR=19.08 (95%CI 7.30-49.82). Risk of pulmonary edema rose in patients with drug or alcohol addiction (OR=24.16; 95%CI 8.07-72.34), malignancy (OR=8.97; 95%CI 1.94-41.49), diabetes mellitus (OR=4.04; 95%CI 1.48-11.01), diseases of nervous (OR=4.04; 95%CI 1.17-13.94), urinary (OR=3.39; 95%CI 1.33-8.64) and cardiovascular (OR=2.29, 95%CI 0.98-5.34) systems. Higher risk of death in patients with CAP was associated with the presence of cardiovascular diseases (OR=2.17; 95%CI 1.11-4.25), diabetes mellitus (OR=2.95; 95%CI 1.20-7.21), drug or alcohol addiction (OR=38.40; 95%CI 15.05-97.98).
Authors and Affiliations
Y. M. Mostovoy, A. V. Demchuk, T. V. Konstantynovych, K. D. Chichirelo-Konstantynovych
Keywords
Related Articles
- EP ID EP299418
- DOI 10.26641/2307-0404.2018.1(part1).127248
- Views 114
- Downloads 0
Експресія генів нуклеарного фактора активованих Т-клітин у дітей з двостулковим аортальним клапаном серця
Гены нуклеарного фактора активированных Т- клеток (NFATC) играют ключевую роль как в формировании клапанов сердца, та и в имуннном ответе. В экспериментальных моделях также показано, что данные гены, относящиеся к факто...
Исследование эффективности оперативного лечения хронических дакриоциститов – эндоназальной дакриоцисториностомии
Дослідження ефективності оперативного лікування хронічних дакріоциститів - ендоназальної дакріоцисториностомії. Бородуля В.Л., Гречка О.М., Степахіна М.Е., Дербіна О.А. Тривала й постійна сльозотеча (симптом епіфори) вик...
Dynamics of parameters of elastic-elastic properties of arterial wall in patients with morbid obesity after conduction of bariatric treatment
According to the World Health Organization, 2.8 million people die every year from diseases associated with overweight or obesity. Abdominal-visceral form is a serious predictor of mortality from cardiovascular disease....
The role of assessment of quality of life and health with the index of vital activity in patients with arterial hypertension combined with gout in the family doctor practice
The number of studies that assess the quality of life of patients with various comorbid diseases is increasing annually. Arterial hypertension and gout is no exception. There are difficulties in managing this category of...
Hygienic estimation of occupational risk and substantiation of regulations on Orvego Fungicide safe application in agricultural sector
Hygienic evaluation of labour conditions during Orvego pesticide application on grapes and onion was carried out and content of ametoctradin and dimethomorp in the working zone air, atmospheric air, and the soil wa...