Clinical and Genetic Aspects of Oral Lichen Planus

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Clinical and Genetic Aspects of Oral Lichen Planus

Journal Title: International Journal of Biomedical and Advance Research - Year 2016, Vol 7, Issue 6

Abstract

Lichen planus (LP) is a chronic inflammatory muco-cutaneous disease. Oral Lichen Planus (OLP) is often asymptomatic; the atrophic-erosive form can cause symptoms ranging from burning sensation to severe pain, interfering with speaking, eating, and swallowing. OLP can be a source of severe morbidity and has a small potential to be malignant. The prevalence of OLP varies from 0.5% to 4% of the general population and in spite of extensive research; exact etiology of OLP remains unclear. A proper understanding of the clinical presentation, pathogenesis and diagnosis of the disease becomes important for providing the right treatment. The present review draws together aspects of Epidemiology, Clinical Features, Etiopathogenesis with emphasis on Genes involved in OLP pathogenesis and the clinical management of OLP.

Authors and Affiliations

Mohammad Akhoondzadeh Haqiqi, Nadia Pourmoshir, Ali Hosseini Bereshneh

Keywords

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EP ID EP364506
DOI 10.7439/ijbar.v7i6.3269
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