Clinical and Histopathological Findings in Elderly Breast Cancer Patients: Single Center Results
Journal Title: Yeni Yuzyil Journal of Medical Sciences - Year 2022, Vol 3, Issue 3
Abstract
Aim: In the literature, there are clinical and histopathological differences in elderly breast cancer patients compared to younger patients. In our study, we compared elderly breast cancer patients treated in our hospital with younger patients in terms of clinical and histopathological features. Material and Methods: In our study, the results of breast cancer patients treated between 01.01.2018 and 31.07.2021, Sancaktepe Martyr Prof. Dr. İlhan Varank Training and Research Hospital was evaluated retrospectively after the approval of the Ethics Committee dated 27/10/2021 and numbered 2021-1999. The clinical features, histopathological findings and surgical treatment methods of the patients were evaluated from their personal files. The patients were evaluated by dividing them into young and old patient groups, and 65 years was determined as the threshold value for the separation of young and old patients. Results: 142 female breast cancer patients were included in our study, 103 (72.53%) were younger than 65 years old and 39 (27.47%) were older than 65 years old. The presence of co-morbid disease was significantly higher in the elderly patient group than in the younger patient group (p=0.0001). It was observed that the diagnosis of breast cancer was mostly made with clinical findings in both young and old patient groups, routine breast screening remained in the background, and large tumor size and lymph node positivity were encountered in both groups. ER and PR receptor positive, luminal type A, grade II and III tumors and invasive ductal carcinomas with Ki 67 >15% were detected in elderly patients. Compared to the younger patients in our study, papillary carcinoma was significantly more common in elderly patients. Among the surgical treatments applied to elderly patients, axillary sentinel lymph node sampling and breast-conserving surgical treatment techniques were observed most frequently. Discussion and Conclusion: We believe that the importance of breast cancer screening programs for young and old women should be increased and treatment protocols for older breast cancer patients should be determined by taking into account geriatric risks.
Authors and Affiliations
Nihan TURHAN, Didem ERTORUL, Dilek YILMAZ, Şafak COŞKUN, Elbrus ZARBALİYEV
Keywords
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- EP ID EP713807
- DOI https://doi.org/10.46629/JMS.2022.92
- Views 57
- Downloads 0
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