CLINICAL AND HISTOPATHOLOGICAL PROFILE OF PATIENT WITH SOLITARY THYROID NODULE IN TERTIARY CARE HOSPITAL IN SOUTH INDIA
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2017, Vol 6, Issue 89
Abstract
BACKGROUND Incidence of malignancy in a solitary thyroid nodule is higher than in multinodular goitre. The prevalence of nodules in the general population is around 8% with greater predisposition in females. This study was undertaken to study the functional status of solitary nodules and to analyse the types of malignancy occurring in solitary nodules. MATERIALS AND METHODS This cross-sectional study was done among patients who presented with anterior neck swelling and diagnosed as Solitary Thyroid Nodule in SRM Medical College Hospital and Research Centre, SRM Nagar, Kattankulathur, Kancheepuram Dist., Tamilnadu. Clinical, laboratory and histopathological evaluation of patients was done for confirmation of findings. RESULTS Total of 50 cases of Solitary Thyroid Nodule were studied. The age of the patients ranged from 22 years to 66 years (Mean age= 38.44 years). Solitary Nodule of Thyroid was more common in females. The distribution of nodule either on right or left side was almost equal. The size of the nodule varied from 2 cm to 7 cm. Most patients (38) presented with a size between 2 to 4 cm. Based on histopathological confirmation 4 out of the 50 patients were found to have malignancy, which comprised 8% of the study population. Follicular adenoma was present in 24% of the patients. Adenomatous goitre was present in 62% of the patients and simple cysts in 2% of the patients. CONCLUSION This study shows that Solitary Nodule of Thyroid is more common in females and in 3rd to 5th decades of their age. Incidence of Malignancy in Solitary Nodule of Thyroid is 8%. Histopathology reports proved that Papillary Carcinoma is most common malignancy in patients with solitary nodule.
Authors and Affiliations
Mohamed Musthafa S, Mahadevan D. S. A, Rajesh Daniel, Rahul Rai, Pari Vallal D, Lokesh Reddy M, Abhinav Bharadwaj R
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