Clinical and OCT features of different types and stages of diabetic optic neuropathy
Journal Title: Офтальмологический журнал - Year 2018, Vol 0, Issue 1
Abstract
Background: The advent of optical coherence tomography (OCT) has offered new opportunities for differential diagnosis of diabetic optic neuropathy (DON). Purpose: To identify clinical and OCT features of different types and stages of DON. Materials and Methods: A total of 575 patients (1150 eyes) with type 2 diabetes mellitus (T2DM) were included in the prospective analysis of the features of optic nerve damage. For comparison, we used data from a group of 50 age- and sex-matched healthy control patients. In addition to routine ocular examination, patients underwent ophthalmochromoscopy, OCT of the retina and optic nerve, and electrical physiological studies. Results: In diabetic papillopathy, anterior ischemic DON, and degenerative-, advanced-, mild-, and subclinical-stage axial DON groups, mean ganglion cell complex focal loss volume values were 21.7, 20.5, 17.3, 13.4, 10.3, and 7.5 times higher, respectively, than in controls. In diabetic papillopathy, anterior ischemic DON, and advanced-stage axial DON groups, mean peripapillary retinal thickness values were 92.2%, 84.7%, and 38.7% higher, respectively, than in controls, whereas in subclinical-, mild-, and degenerative-stage axial DON groups, the values were 8.0%, 13.8%, and 20.5% lower, respectively, than in controls. Conclusion: We have identified clinical and OCT features of different types and stages of DON in patients with T2DM.
Authors and Affiliations
P. Bezditko, M. Karliychuk
Keywords
Related Articles
- EP ID EP268939
- DOI -
- Views 117
- Downloads 0
Clinical efficacy of treatment for subclinical-stage axial diabetic optic neuropathy
Background: There is no standard of therapy for the treatment of diabetic optic neuropathy (DON). Purpose: To assess the clinical efficacy of thioctic acid, topical brimonidine tartrate and a combination of vitamins В1,...
Modelling form deprivation myopia in experiment
Background. Myopia, leading to visual function impairment, is one of the most topical issues in eye pathology. Although myopia is a common disease, its pathogenesis has a set of questions unstudied, which is why it is cr...
Surgical management of bilateral congenital coloboma of the iris and congenital cataract
Background. A combined character of a defect, which is congenital coloboma in the presence of congenital cataract, brings up an issue of choosing optimal management to achieve the maximum possible optical functions, prov...
Retinal injuries secondary to consumer laser devices in children
Background: In recent years, increased incidence of retinal injuries secondary to consumer laser devices (predominantly, pointers and those used at disco clubs) in children and adolescents have been observed. Purpose: T...
Effect of colloidal silver nanoparticle solution instillation on the ultrastructure of the corneal epithelium and stroma
Introduction. Existing methods of treatment for bacterial keratitis do not always provide a positive therapeutic effect and do not prevent the occurrence of relapses. The main reason for this is the development of resist...