CLINICAL AND PATHOLOGICAL SIMILARITIES BETWEEN PARATUBERCULOSIS AND CROHN’S DISEASE. ¿A POSSIBLE ZOONOTIC LINK?
Journal Title: Revista MVZ Cordoba - Year 2008, Vol 13, Issue 1
Abstract
This review assesses the evidence for an association between Mycobacterium avium subspecies paratuberculosis (MAP) and Crohn’s disease and describes the main clinical and pathological similarities. The review is limited to publications contained in the program HINARI of the WHO, especially Elsevier Science, International Bioline, Blackwell Publishing, BMJ Publishing, Lippincott Williams & Wilkins, Nature Publishing, PubMed, Springer Science and publications of the International Association for study of Paratuberculosis. Evidence supporting a link between these diseases include the isolation of Mycobacterium avium subspecies paratuberculosis from intestine, milk, peripheral blood and lymph nodules of Crohn’s patients and the specific immune response to some Mycobacterium antigens in Crohn’s patients. Nevertheless each of these findings is controversial. The currently available evidence is not sufficient to prove or disprove that Mycobacterium avium subspecies paratuberculosis is a cause of Crohn’s disease, due to the multifactorial nature of this disease, studies do not conclusively allow the acceptance of a zoonotic link. Studies are required to determine if Mycobacterium is only a spectator or a pathogenic agent. In addition, epidemiologic studies are required at a sufficiently large scale to permit analysis of the geographical and temporal distribution of both diseases.
Authors and Affiliations
Johan Calderón, Zoot| 1Práctica Particular., Agustín Góngora O, Ph. D *| Universidad de los Llanos, Escuela de Medicina Veterinaria y Zootecnia, Grupo de Investigación en Reproducción y Genética Animal – GIRGA. Villavicencio, Colombia.Correspondencia: agongora60@hotmail.com
Keywords
Related Articles
- EP ID EP3091
- DOI -
- Views 431
- Downloads 21
LENGTH-WEIGHT RELATIONSHIP OF RUBIO (Salminus affinis Steindachner, 1880) IN THE SINU RIVER BASIN, COLOMBIA
Behavior of the Hydrochoerus hydrochaeris isthmius in a productive system, department of Córdoba, Colombia
Objective. To describe the behavior, of the subspecies H. hydrochaeris isthmius, during the dry and rainy seasons in catlle farms, Valencia, Córdoba, Colombia. Materials and methods. A population of animals between Septe...
Maternal-calf relationships and their influence on calves up to 120 days
Objectives. To research parental behavior and measure the weight of Nelore and Guzerat calves up to 120 days of age, collecting data from birth up to the first lactation. Materials and methods. Seven different corporal p...
Enterotoxigenic Genes in strains of Staphylococcus spp., isolated from cheese made in Pamplona-Colombia
Objective. To determine the incidence of coagulase-positive strains of enterotoxigenic Staphylococcus in doble crema (double cream) cheese samples produced in Pamplona. Materials and methods. Bacterial isolation was perf...
Seasons and planting densities interaction on forage production of eight hybrids maize, Ecuador
Objective. To assess the interaction effect of the season and planting densities on the production of eight INIAP corn hybrids. Materials and methods. A research process was conducted in 2013. It was applied a split - sp...