Clinical Efficacy of Platelet-Rich Plasma on Allograft Transplantation after Core Decompression for Osteonecrosis of the Femoral Head
Journal Title: Journal of Orthopedics & Bone Disorders - Year 2017, Vol 1, Issue 4
Abstract
Purpose: This study explored the outcomes and clinical use of autologous, platelet-rich plasma (PRP) infusion after allograft bone transplantation for osteonecrosis of the femoral head (ONFH) by comparing the time to bone fusion and clinical symptoms. Method and Materials: From January 2008 to June 2015, 36 patients with a follow-up of at least 12 months were enrolled. 18 who underwent autologous PRP infusion after allograft bone transplantation were compared with 18 who underwent allograft bone transplantation only. Changes in pain and activities of daily living were assessed by a visual analog scale (VAS), the Harris Hip Score (HHS) and the time to bone fusion respectively, to evaluate differences between the two groups. Results: The VAS scores of patients who underwent autologous, PRP infusion was significantly improved compared to patients who did not undergo autologous, PRP infusion at post-operative 3 months(From 7.44 to 3.28 in PRP/ From 7.06 to 5.67 without PRP), but not at post-operative 12 months(From 7.44 to 6.95 / From 7.06 to 7.00). The HHS which showed no significant difference between groups(75 / 76). The mean time to bone fusion was 3.0 months (range, 1.5 to 5.7 months) in PRP group and 5.5 months (4.0 to 8.0 months) in without PRP group. Conclusion: Autologous, PRP infusion after allograft bone transplantation of core decompression for ONFH can promote bone fusion and initially produces effective pain control. However, the natural progression of disease, including femoral epiphyseal depression or osteonecrosis of the femoral head, is unlikely to be affected.
Authors and Affiliations
Baek S and Chung SH*
Keywords
Related Articles
- EP ID EP752095
- DOI -
- Views 59
- Downloads 0
ISSN: 2577-297X Research Article Upper Limb Non-Traumatic Affections in a Rural Tertiary Health Care Center
Introduction: Non-traumatic upper limb disorders are not uncommon. These may range from non-specific myalgia & fibro-fasciitis to specific disorders of joints and bones of the upper limb bones. Frequent key board use is...
Medial Epicondyle Fractures of Humerus in Children at the University Teaching Hospital of Yopougon
The purpose of this study is to evaluate the results of surgical treatment of medial epicondyle fractures in children. Patients and Methods: A retrospective study of 17 children was performed in the Pediatric Surgery Dep...
Lateral Condyle Fracture Dislocation of the Elbow Joint in an Adult: A Rare Case Report
Fracture dislocation of the humeral condyle is very rare in adults. There are only two published studies in the world literature demonstratingsuch injury. Plan of management for this injury is still not well defined. We...
The Treatment of Open Debridement to the Glenohumeral Joint Osteoarthritis
Aim: To explore the effect of open debridement to the glenohumeral joint osteoarthritis. Methods：Open debridement was applied to treat 16 cases of glenohumeral joint osteoarthritis from March 2014 to June 2015. Results:...
Prevalence of Paediatric Fractures in Teaching Department of Orthopaedics and Musculoskeletal Trauma in Eastern Slovakia during the Year 2018
Objective: To determine the prevalence of different fractures among paediatric age 0-19 years in teaching department of orthopaedics and musculoskeletal trauma during one year. Methods: We retrospectively evaluated all c...