Clinical Features of Suspected CNS Infection in A Tertiary Care Center
Journal Title: Journal of Medical Science And clinical Research - Year 2016, Vol 4, Issue 11
Abstract
Background: Infections of the central nervous system are neurological emergencies requiring early recognition and efficient decision making. Clinical presentations are varied and non infective causes can also present with similar features. Aim and Objectives: To study the causes of altered sensorium and to analyze the profile of patients presenting with CNS infection. Methods: The study included 121 patients (73 males and 48 females) who met inclusion criteria (Age more than or equal to 18 years and suspicion of CNS infection) admitted in Sri Ramachandra Medical College Hospital from the year 2009 to 2011. Clinical presentations were analyzed by questionnaire and detailed examination including a fundoscopy done. Results: Out of 121 patients, 90 had CNS infection. 15 patients had bacterial meningitis, 32 had tuberculous meningitis, 9 had aseptic meningitis, 30 had encephalitis and 4 had Cryptococcal meningitis. Viral encephalitis was seen more in younger age group. The most common presenting symptom was fever (105 patients), followed by altered sensorium (89), headache in (68), vomiting in (58) and seizures in 48 patients. Altered sensorium was universal in cryptococcal meningitis. 45.5% of patients with CNS infection presented with seizures while 35.5% had seizures in patients without infection. Mean duration of fever was 23 days for cryptococcal meningitis with TB meningitis having 15 days. 75% patients had neck stiffness and focal neurological deficits were seen in 9% patients. Fundus was abnormal in 28.1 % patients. Conclusion: Clinical presentation of CNS infections is a changing scenario. Young patients had more incidence. Fever and altered sensorium were the most common symptom. Neck stiffness was not an universal feature.
Authors and Affiliations
Yeldho Verghese
Keywords
Related Articles
- EP ID EP214843
- DOI -
- Views 80
- Downloads 0
Expression of Stathmin and CD10 in Invasive Mammary Carcinoma with Relation to Triple Markers
Background: Stathmin is a highly conserved cytosolic phosphoprotein that destabilizes microtubules. Stathmin acts in vitro as a tubulin-sequestering protein, and its activity is dramatically reduced by phosphorylation. I...
Compendium of Urinalysis – Urine Reagent Strips and Microscopy
Background: Urine examination also referred to as liquid renal biopsy has provided valuable clinical information about the functional status of the kidney. These results can be relied for a number of applications, includ...
Uterine Myoma, Epidemiology, Pathophysiologic, Reproductive, Clinical and Therapeutic
The Uterine leiomyomas are benign smooth muscle tumors of slow growth, most patients are asymptomatic or discovered during a routine gynecological examination. Clinical manifestations occur in 20-40% with abnormal uterin...
A Prevalence of Hypertension in Children – School Based Study
Objectives: To study the prevalence and aetiology of Hypertension in school children aged 10-15 Years. Methods: In this study 975 students from 3 Govt. Schools and 975 Students from 4 Pvt. Schools of age group of 10 – 15...
Comparison of Colour Doppler Flow Imaging with Voiding Cystourethrography in the Detection of Vesicoureteric Reflux in Children
Introduction: Early detection and management of Vesicoureteric reflux (VUR) prevents the adverse renal effects. Voiding cystourethrography (VCUG) is considered the gold standard for diagnosis of VUR. Colour Doppler flow...