CLINICAL PROFILE AND OUTCOME OF PARAQUAT POISONING INDUCED ACUTE KIDNEY INJURY
Journal Title: IJAR-Indian Journal of Applied Research - Year 2018, Vol 8, Issue 8
Abstract
Paraquat poisoning is one of the causes of AKI, the mechanism of toxicity being the production of reactive oxygen species, thereby causing toxicity at the cellular level. The aim of this study was to determine the requirement of haemodialysis and the severity of toxicity, depending upon the amount ingested. It was found that in Paraquat poisoning, the intervention with preemptive haemodialysis was not useful in decreasing the mortality. Ingestion under the influence of alcohol had higher mortality. Amount of poison ingested had a great impact and was directly proportional to the mortality. Oral ulcers, hepatic involvement, ARDS and MODS all reflected grave prognosis ultimately leading to death. The overall mortality in the study was 51%.
Authors and Affiliations
Dr. A. Jegan, Dr. R. Arul, Dr. P. Arun Prasath, Dr. P. Krishnananth, Dr. C. Madhusuthanan
Keywords
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