CLINICAL PROFILE OF DENGUE FEVER IN PAEDIATRIC PATIENTS IN A TERTIARY CARE HOSPITAL
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2017, Vol 6, Issue 92
Abstract
Prevalence of dengue has been steadily increasing over last few years in South East Asia including India. Increased number of epidemics has been reported in last few years (WHO 2008). Usually dengue viral infection is self-limiting but complications may cause high morbidity and mortality. Case fatality rate has been reported around 1 percent. Objectives1. To assess the clinical profile of dengue infection in children less than 12 years. 2. To study the epidemiology and evaluate the outcome of dengue fever. MATERIALS AND METHODS A retrospective-descriptive design was adopted. Indoor record papers of patients admitted with confirmed dengue cases in paediatric ward from October 2016 to September 2017 were studied. Dengue NS1 antigen, dengue IgM and IgG were taken as confirmation of dengue infection. RESULTS Out of 117 cases, 78 were male and 39 were female. Maximum number of cases were seen in the age group of 4-12 years. In our study as per WHO classification, we have categorised 43 children with dengue without warning signs, 59 dengue with warning signs and 15 severe dengue. Fever was seen in 100% cases. Among children with warning signs, predominant features noted were puffiness of face (38%), abdominal distention (30%), abdominal pain (27%), and headache (26%). Hepatomegaly was seen in 50.42%. In severe dengue category, 6 (40%) had bleeding, 4 (26.66%) had CNS involvement, 4 (26.66%) had bilateral pleural effusion and 1 (6.66%) had intractable shock. Laboratory parameters seen were, raised haematocrit (64.95%), leucopenia (47.86%) and thrombocytopenia (69.23%). Blood transfusion was given in 2 patients and platelet transfusion was given in 2 patients. 1 (0.85%) patient died. CONCLUSION Dengue is commonly seen in children in the age group of 4-12 years. Signs of plasma leak are reliable indicators of the severity of disease. Laboratory parameters like leucopenia, raised haematocrit and thrombocytopenia along with raised SGOT were strongly associated with risk of developing complications. Early institution of fluid therapy according to WHO guidelines, results in favourable outcome.
Authors and Affiliations
Shailaja Potdar, Sunil Junagade, Jayesh Panot, Vandana Kumavat, Mohit V Rojekar, Krutika Thakur
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