Clinical Study of Neonatal Septicemia with Reference to Early Indicators of Sepsis in NICU, PIMS
Journal Title: Pediatric Education and Research - Year 2017, Vol 5, Issue 3
Abstract
Neonatal septicaemia is a major cause of morbidity and mortality in new born infants. Back ground and objectives: to study the incidence, predisposing factors, clinical profile, out come, early indicators of correlation with all clinical aspects and antibiotic sensitivity pattern of neonatal septicaemia. Materials and Methods: The 50 neonates who are showing the well documented signs of septicaemia are included in this study. Results: culture was bacteriologically positive in 34% cases. Ciprofloxacin had maximum sensitivity 88.2%. Leucopoenia £5000/cmm had sensitivity of 47% specificity of 66.67% and ppa of 42.11%,toxic granulation had 70.56% sensitivity, 63.65% specificity and 50% ppa. B/n>0.2 had 88.2% sensitivity 62.4% ppa. m-ESR had sensitivity of 70.56%, specificity of 84.84%, ppa of 70.5%, c-reactive protein had 88.2% sensitivity and 87.8% specificity and 78.95%ppa. Case fatality rate was 28%. Conclusion: Clinical features of neonatal septicaemia are non specific and vague. Sepsis screen had good sensitivity, specificity and ppa. combination of tests increase the specificity and ppa. An an individual test c- reactive protein has highest sensitivity.
Authors and Affiliations
Vamshi Krishna Kondle
Keywords
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- EP ID EP475573
- DOI 10.21088/per.2321.1644.5317.7
- Views 105
- Downloads 0
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