CLINICO-EPIDEMIOLOGICAL STUDY OF CUTANEOUS ADVERSE DRUG REACTIONS: A HOSPITAL-BASED STUDY
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2019, Vol 6, Issue 31
Abstract
BACKGROUND Cutaneous drug reactions are the most common adverse reactions attributed to drugs. They often mimic or cause common cutaneous reaction patterns such as bullous disorders, lichen planus, psoriasis, eczema etc., METHODS It was a hospital based cross sectional study including 140 clinically diagnosed cases of Cutaneous Adverse Drug Reaction (CADR). Demographic details, clinical patterns, types of drugs and causality assessment were studied in each one of them. RESULTS Most common age group to have CADR was 21-40 years. The male to female ratio was 2.25:1. Fixed Drug Eruption including the bullous variant was the commonest, seen in 45.71% patients and followed by maculopapular rash in 17.14% and Stevens Johnson Syndrome (SJS) in 11.42%. The commonest offending group of drug as a whole was Antimicrobials (54.3%) followed by Non-Steroidal Anti Inflammatory Drugs (NSAID) (37.85%) and Antiepileptics (5.71%). CONCLUSIONS CADR commonly presents as Fixed Drug Eruption or maculopapular lesions and commonly implicated drugs are Antimicrobials, NSAIDs and Anti-Epileptics.
Authors and Affiliations
Satyendra Kumar Sharma, Tanmay Padhi
Keywords
Related Articles
- EP ID EP670407
- DOI 10.18410/jebmh/2019/430
- Views 106
- Downloads 0
SURGICAL APPROACH TO ABDOMINAL TUBERCULOSIS
BACKGROUND Tuberculosis is one of the common diseases in developing countries, extrapulmonary tuberculosis is common in gastrointestinal system. Surgical intervention is required along with chemotherapy, ultrasonography...
ENT MANIFESTATIONS IN HEREDITARY HEMORRHAGIC TELANGIECTASIA: A CASE REPORT
Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant disorder, which affects various internal organs and has a tendency for bleeding. It has a classic triad of mucocutaneous telangiectasias, recurrent hem...
PREVALENCE OF H. PYLORI IN DUODENAL ULCER PERFORATION
BACKGROUND Duodenal ulcer perforation is among common surgical emergencies. Recent data suggests that more than 99% of all duodenal ulcers having infection with H. pylori is associated with use of NSAIDS. There is a nece...
TUBERCULOSIS AND HIV COINFECTION: A TERTIARY CARE HOSPITAL STUDY
OBJECTIVE The aim of the present study is to record the clinical, radiological profile of pulmonary and extra pulmonary tuberculosis (EPTB) in HIV positive patients. To win the battle against AIDS we have to fight agains...
A STUDY OF SERUM HYPOMAGNESIUM LEVELS IN ACUTE MYOCARDIAL INFARCTION
There are reports in the literature over patients with acute myocardial infarction, who have low lower magnesium levels. Results of clinical, laboratory and epidemiological studies indicate that the association between m...