CLINICOHEMATOLOGICAL PROFILES OF HEPATITIS A VIRUS (HAV): A RETROSPECTIVE STUDY
Journal Title: International Journal of Medical Laboratory Research - Year 2018, Vol 3, Issue 1
Abstract
Aim: Acute viral hepatitis A (HAV) is a major problem in parts of the developing countries. HAV is transmitted enterically and its incidence is high in places where poor hygienic conditions prevail. Most studies in the past have been on liver the primary organ affected by HAV and reports on extrahepatic organs are lacking. The present study was carried out to ascertain the alterations on the haematological, hepatic and renal parameters. Material and Methods: This was a retrospective study and was conducted in a tertiary care hospital in India. Data was analysed in people who expressed known symptoms of HAV and established by Anti-HAV IgM antibody. A total of 22 paediatric and 109 adult people were included in the study and compared with healthy individuals who were tested negative for infectious and chronic diseases. Results: The results indicated that jaundice, vomiting and fever were the predominant clinical symptom seen in both children and adults. There was significant difference in the various haematological, hepatic and electrolyte endpoints (p < 0.05 to 0.0001), while there was no such difference in the renal function test parameters. Conclusion: The present study indicates that acute infection with HAV causes alterations in haematological, hepatic parameters and in the levels of electrolytes in the serum.
Authors and Affiliations
Ramakrishna Pai Jakribettu, Thomas George, Rashmi Mathai, Muhammad Adnan, Taresh Naik, Manjeshwar Shrinath Baliga
Keywords
Related Articles
- EP ID EP278463
- DOI -
- Views 129
- Downloads 0
ALTERATIONS IN HEMATOLOGICAL, LIVER AND RENAL PARAMETER LEVELS IN PEOPLE AFFLICTED WITH LUNG CANCER
Background: Lung cancer is one of the most cancers in the world. It has a bad prognosis and is associated with high cancer related mortality. The present study was carried out to ascertain the alterations in the haematol...
CLINICOHEMATOLOGICAL PROFILES OF HEPATITIS C VIRUS (HCV): A RETROSPECTIVE HOSPITAL BASED STUDY
Aim: Acute viral hepatitis C (HAC) is an important organ specific virus affecting the liver. The pathological sequelae of the infection are well documented and a detailed literature study indicates that most studies have...
CROSS INFECTIONS WITH BACTERIAL CONTAMINATED HANDS DURING ROUTINE CARE IN MEDICAL WARDS.
Health worker’s hands though not totally free from microorganisms, are more contaminated with microbial pathogens during routine care on patients attending to treatments. These contaminated hands thereafter transferred p...
IS RESISTANCE TO ETHIONAMIDE AN EXTRAPOLATION OF OTHER FIRST AND SECOND LINE ANTI- TUBERCULOSIS DRUGS?
Drug Susceptibility profile of ethionamide and other first and second line anti tuberculosis drugs revealed no significant association, indicating the resistance towards ethionamide is the result of individual effect and...
OUTCOME OF IMPLEMENTATION OF HOSPITAL INFECTION CONTROL GUIDELINES ON THE ANTIBIOTIC RESISTANCE PATTERN IN STAPHYLOCOCCUS AUREUS ISOLATED FROM SKIN AND SOFT TISSUE INFECTIONS: A RETROSPECTIVE TWO TIME POINT STUDY
BACKGROUND: Skin and soft tissue infections (SSTIs), by Staphylococcus aureus is a commonly observed phenomena. However, when the organism is methicillin-resistant S. aureus (MRSA) the morbidity is high and the organism...