Clinicoradiological Evaluation of Newly Diagnosed Epilepsy: A Monocentric Prospective Study from a Tertiary Care Hospital of Eastern India
Journal Title: Journal of Clinical and Diagnostic Research - Year 2018, Vol 12, Issue 2
Abstract
ABSTRACT Introduction: Newly Diagnosed Epilepsy (NDE) is defined as a subset of epileptic disorders, which is presented or diagnosed first time during study period and had two or more than two episodes of seizure. Early evaluation and diagnosis of epilepsy is very important for better treatment. Aim: To evaluate epidemiological, clinical profile as well as radiologic characteristics in cases of NDE and to find out correlation between them. Materials and Methods: It was a prospective and descriptive study of three year duration conducted in the Department of Neurology in SCB Medical College and Hospital, Cuttack, Odisha, India. A total of 300 NDE patients more than five years of age were included and subjected to detailed clinical and radiological evaluation. Results: Majority patients in our study were from second and third decade (mean age 25 years, SD=11.04) with characteristic male preponderance. Most patients were from rural background and majority of them (60%) had attended Neurology clinic after three to 10 episodes of seizures. Seizures in awake state and seizures without precipitating factors were more common. Headache was the most common prodromal symptom. Generalised seizure dominated over focal seizure (62:34) with tonic-clonic type (66.67%) being most common in the generalised seizure cohort. Focal seizure with secondary generalisation was seen in 70.5% cases. Drowsiness (38%) and Todd’s Palsy (6%) were most and least common postictal symptoms in our study. Our study also revealed abnormal Computed Tomography (CT) findings in 70.6% of focal seizures and 24.2% of generalised seizures. MRI, though done in 250 patients only, 53.6% were abnormal. Granulomatous lesion was dominant neuroimaging finding in our study. Conclusion: This study concluded that males of second and third decade from rural background are highly prone to epilepsy. Infectious causes like Neurocysticercosis (NCC) and tuberculoma are predominant aetiologies in our area. Neuroimaging plays an important role in establishing and localising aetiology of seizure. Any patient coming with history of epilepsy must be investigated with neuroimaging for further management.
Authors and Affiliations
MAHESWAR SAMANTA, ASHOK KUMAR MALLICK, GEETA MOHANTY, KALI PRASANNA SWAIN
Keywords
Related Articles
- EP ID EP515983
- DOI 10.7860/JCDR/2018/29988.11172
- Views 78
- Downloads 0
Muscle Activation Profiles and CoActivation of Quadriceps and Hamstring Muscles around Knee Joint in Indian Primary Osteoarthritis Knee Patients
Introduction: Osteoarthritis (OA) of knee is a common joint disease. It is associated with reduced knee joint stability due to impaired quadriceps strength, pain, and an altered joint structure. There is altered muscle a...
Musculoskeletal Disorders and Quality of Life of Sugarcane Farmers in the Northeast of Thailand: A Cross-sectional Analytical Study
ABSTRACT Introduction: Musculoskeletal Disorders (MSDs) were directly associated with Quality of Life (QOL). It could cause various adverse consequences to daily life function, psychological health, work capacity and inc...
Effect of Punica granatum Extract Gel on Gingival Crevicular Fluid Levels of Interleukin1β, Interleukin-8 and CCL28 Levels: Randomised Controlled Clinical Trial
Introduction: Pomegranate (Punica granatum) fruit extract has anti-inflammatory, anti-bacterial, anti-oxidant and immunemodulatory features. Due to increased bacterial resistance to synthetic agents Pomegranate Extract G...
Isolated Traumatic Chronic Anterior Dislocation of Radial Head
Isolated traumatic anterior radial head dislocation is extremely rare and very commonly missed injury. A 12-year-old male had a fall on outstretched hand with pronated forearm. He presented after 6 weeks with complaints...
Dental Students’ Perception of Dentine Hypersensitivity and Awareness about its Management
ABSTRACT Introduction: Dentine hypersensitivity is a common painful oral condition that can interfere with drinking, eating, tooth brushing and even breathing. Successful management depends on the identification and elim...