Coagulation Profiles an Indicator of Vascular Haemostatic Function in Chronic Renal Failure Patients Who Are on Renal Dialysis.
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2014, Vol 2, Issue 2
Abstract
Renal disease is a common cause of death and disability in many countries throughout the world. Renal failure can be classified as acute and chronic depending upon the etiological factors. Chronic kidney disease (CKD) is a common threat to critically ill patients in intensive care units with a mortality rate ranging from 42% to 88%. Treatment methods such as dialysis and transplantation are becoming more effective in life threatening conditions. To assess the coagulation profile level in chronic renal failure patients who are on haemodialysis and comparison was made with age matched controls. Totally 50 members were selected for the study. Among them 25members were chronic renal failure patients (Group A) and 25 members were normal healthy subjects served as controls (Group B). Both the groups were age matched and comparison of coagulation profile was done. Parameters analysed in the study are Platelet count (Pl), Prothrombin time (PT), international normalization ration (INR), Activated Prothrombin time (APTT), Plasma fibrinogen (PF). From our study we concluded that Prothrombin time, INR, Activated Prothrombin time, Plasma fibrinogen level were increased in chronic renal failure patients(Group A) when compared to control (Group B). Platelet count was found be increased in control (Group B) when compared to chronic renal failure patients (Group A). Coagulation profiles has a significant variations in chronic renal failure. This leads to lot of complications such as sepsis, massive tissue repair and obstruction in vascular compartment. Regular monitoring of anticoagulant doses and haemodialysis may minimise the risk of vascular injury.
Authors and Affiliations
Ramaprabha P, Bhuvaneswari T, R. Aravind Kumar
Keywords
Related Articles
- EP ID EP374236
- DOI -
- Views 76
- Downloads 0
Ameloblastoma –A Case Report with a Systematic Review on Pathogenesis and Recent Trends in Radiographic Assessment
Abstract: Ameloblastomas a common odontogenic neoplasm is a locally aggressive tumour of the jaw has an unknown etiology but commonly arises from the lining of epithelium of odontogenic cysts, remnants of odontogenic epi...
Squamous cell carcinoma of skin and primary adenocarcinoma of the colon: a case report with review of literature
Colorectal adenocarcinoma may demonstrate familial association with cancers at other sites. Herein, we reported a case report with SCC of the skin and colon cancer in the West of Iran. On July 2015, a 44-year man referre...
Evaluation of lipid profile status in nondiabetic and diabetic hypothyroidism patients
In the last few decades, abnormality in lipid profile is a serious concern in various diseases including diabetes mellitus. However, limited studies have been documented on lipid abnormality in hypothyroidism (HT) along...
Ultrasonographic Evaluation of Gynecological Pelvic Masses - An Observational Study
Abstract: Pelvic ultrasound is commonly used as part of the routine gynecologic exams, resulting in diagnosis of adnexal masses, the majority of which are functional or benign. However, due to the possible complications...
Study of Etiology and Prevalence of Non-Adherence to Treatment in Patients with Inflammatory Bowel Disease Referring to Gastroenterology Clinic of Imam Khomeini Hospital in Ahvaz and Private Gastroenterology Clinics in 2016
Abstract:This study was conducted to determine etiology and prevalence of non-adherence to treatment in patients with inflammatory bowel disease referred to the gastroenterology clinic of Imam Khomeini Hospital in Ahvaz...