Coconut Oil as an Adjuvant to Magnesium Sulphate Therapy in Acute Aluminum Phosphide Consumption
Journal Title: International Journal of Anesthesiology & Research (IJAR) - Year 2018, Vol 6, Issue 2
Abstract
Objective: Aluminium phosphide (ALP) poisoning is becoming a serious health care problem in India. It has high mortality rate in spite of aggressive intensive management. Aim: This study is designed to assess the effect of prolonged and multiple dose of coconut oil as adjuvant to magnesium sulphate along with supportive therapy in ALP poisoning patients. Method: Prospective randomized clinical trial on ALP poisoning patients admitted in ICU of tertiary care institution. 50 (25 cases in each group) patients of ALP poisoning, confirmed by history and symptoms of ALP poisoning were included in the studied. Group A received multiple dose of coconut oil through ryles tube for 48 hours along with magnesium sulphate (MgSO4 ) infusion, Group B received only MgSO4 infusion with supportive therapy in both the groups. Patients were assessed for number of tablets consumed, delay in reaching hospital, cardiac symptoms, acidosis (Ph), requirement of vasoactive drugs, need of mechanical ventilation and outcome of patients. Results: Mean dose of aluminium phosphate was 1.7gm and delay in reaching hospital ranging from 3.16 - 4.16 hrs (p= 0.036). Cardiac symptoms were lower in Group A (74 %) Comparing to Group B (100%) (p=0.001), Less acidosis seen in Group A Compared to Group B (p=0.001). The mortality rate in Group A (30%) was less comparison to Group B (60%). Conclusion: Multiple dose of coconut oil for 48 hours through ryles tube along with MGSO4 infusion in ALP poisoning patients has beneficial effect on the management and ultimate favourable outcome of the patients.
Authors and Affiliations
Satish Kumar M N
Keywords
Related Articles
- EP ID EP516738
- DOI 10.19070/2332-2780-18000102
- Views 93
- Downloads 0
Anesthetic Consideration For Laparoscopic Surgery
Minimally invasive surgical procedures aim to minimize the tissue trauma but still achieve a satisfactory therapeutic result. Tissue trauma is significantly less than conventional open procedure. Laparoscopy is the proce...
Comparative Study Between Ketamine–Propofol and Butorphanol - Propofol For Ease of Laryngeal Mask Airway Insertion in Short Surgical Procedures
Back ground: Today LMA has an established role as an airway device for elective surgeries as it offers advantage over tracheal tube with respect to lesser depth of anesthetic needed, allows avoidance of usage of muscle r...
Laparoscopic Guided Transversus Abdominus Plane (Tap) Block – A Modified Technique
We present a modified laparoscopic technique to administer quick and effective Tansversesus Abdominus Plane (TAP) block. The technique combines the benefit of laparoscopic guidance along with the knowledge of radiologica...
Identifying Surgery and Anesthesia - Related Anxiety in Patients Undergoing Colorectal Cancer Surgery
Objective: In patients where colorectal cancer surgery is planned, anxiety is triggered not only by cancer diagnosis, but also potentially by the surgery and anesthesia preoperatively. We aimed to determine preoperative...
Acromegaly, Endocrine Dysfunction and Polyostotic Fibrous Dysplasia Associated With Mccune-Albright Syndrome: Anesthetic Considerations
McCune-Albright Syndrome is a rare disorder affecting the skin, bones and endocrine tissues. It is characterized by the presence of café au lait spots, polyostotic fibrous dysplasia, and autonomous endocrine hyperfunctio...