COMBINATION TECHNOLOGY FOR TREATMENT OF HYPERTENSION: A REVIEW
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2013, Vol 4, Issue 2
Abstract
Hypertension, elevated blood pressure, is a noteworthy public health concern worldwide due to its significant contribution to the global health burden and its role as a prominent risk factor for the development of a number of disease processes. The control of blood pressure is required in patients with hypertension to produce the maximum reduction in clinical cardiovascular end points, especially in patients with co-morbidities like diabetes mellitus where more aggressive blood pressure lowering might be beneficial. Recent clinical trials suggest that the approach of using monotherapy for the control of hypertension is not likely to be successful in most patients. Combination therapy may be theoretically favoured by the fact that multiple factors contribute to hypertension, and achieving control of blood pressure with single agent acting through one particular mechanism may not be possible. Combining the drugs makes them available in a convenient dosing format, lower the dose of individual component, thus, reducing the side effects and improving compliance.
Authors and Affiliations
Sarika Pundir , Ashutosh Badola
Keywords
Related Articles
- EP ID EP103892
- DOI -
- Views 117
- Downloads 0
FORMULATION AND EVALUATION OF METAPROLOL SUCCINATE EXTENDED RELEASE PELLETS
The aim and of the present study is to develop a pharmaceutically stable and quality improved formulation of Metoprolol succinate extended release pellets. To achieve this goal various prototype formulation trials were f...
SCREENING OF ANTICONVULSANT ACTIVITY OF KUSHMANDA FRUIT (BENINCASA HISPIDA THUMB) IN ALBINO RATS
The aim of the present study was to evaluate the anticonvulsant activity of juice and aqueous extract of Benincasa hispida Thumb fruit in Albino Rats. Two drug samples were prepared i.e. Benincasa hispida fruit juice and...
COMPARISION BETWEEN THE EFFECT OF AQUEOUS AND METHANOLIC EXTRACTS OF HOLARRHENA ANTIDYSENTERICA BARK AGAINST EXPERIMENTALLY INDUCED INFLAMMATORY BOWEL DISEASE
It has been demonstrated that Holarrhena antidysenterica Wall. (Apocynaceae) is useful as an adjunctive therapy for Inflammatory bowel disease (IBD). However, its effect on ulcerative colitis has not been investigated. I...
DENDRITIC ARCHITECTURE: A NEW TOOL FOR DEVELOPMENT OF NOVEL DRUG DELIVERY SYSTEMS
Dendrimers are composed of a multifunctional core molecule attached to polymer branches. Drugs can be inserted between the branches and held until ‘interactions’ release it. Dendrimers are a new class of three-dimensiona...
VIEW OF SUSHRUTA ON ROGA AND ROGI PARIKSHA FOR THE VYADHIVINISHCHAYA (DIAGNOSIS OF DISEASES)
Complete understanding of science is essential to get mastery and supremacy in clinical methods. Improper observation of patient by physician, which have not been thoroughly described and diseases which have not been dia...