Combination Therapy With Beta Blocker and Inotrope in Decompensated Heart Failure: A Clinical Observation
Journal Title: Heart Research – Open Journal - Year 2017, Vol 4, Issue 1
Abstract
Inotropic support is contemplated in the presence of ongoing end-organ hypoperfusion or refractory symptoms in decompensated heart failure (DHF). However, inotropic agents may cause tachycardia leading to increased myocardial oxygen demand and arrhythmogenesis.1 Introduction of beta blocker (BB) therapy in DHF patients requiring inotrope support is discouraged due to the negative hemodynamic impact of acute BB therapy.2-5 On the other hand, reduction in heart rate by BB therapy results in decreased myocardial oxygen demand and increased ventricular diastolic filling.6,7 Additionally, early introduction of BB therapy improves outcome in heart failure.2
Authors and Affiliations
Abhishek Jaiswal
Keywords
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- EP ID EP558275
- DOI 10.17140/HROJ-4-136
- Views 138
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