COMPARATIVE CHARACTERIZATION OF ANTIOXIDANT PROFILE OF VITAMIN-E AND RED DATES IN PLACEBO AND TESTED GROUPS OF HYPERLIPIDEMIC PATIENTS
Journal Title: UNKNOWN - Year 2019, Vol 4, Issue 3
Abstract
Antioxidants are nutrients that help minimize free-radical damage to the body. Free radicals are highly reactive compounds that are created in the body during normal metabolic functions or introduced from the environment, such as by exposure to pollution and other toxins. Inherently unstable, free radicals contain "extra" energy which they try to reduce by reacting with certain chemicals in the body, which interferes with the cells' ability to function normally. Current study compared antioxidant characteristics of vitamin-E and red Dates. It was placebo-controlled conducted study conducted at general hospital Lahore Pakistan from January 2018 to march 2018. LDL-cholesterol was calculated as total cholesterol- HDL-cholesterol-VLDL-cholesterol;VLDL-cholesterol was measured directly after ultracentrifugation. After one month therapy their post treatment lipid profile was determined and analyzed statistically by using SPSS version 2.2.01 2013. Paired‘t’ test was applied for mean values with SD of the parameters before and after treatment. Results showed highly significant change in LDL-cholesterol of group-II patients but HDL-cholesterol was increased 6.6 mg/dl, still it was significant change with p-value of <0.01. In group-III LDL-cholesterol was decreased 10.9 mg/dl which is significant change with p-value <0.01. HDL-cholesterol in this group was increased 4.2 mg/dl which is non significant with p-value of >0.05. Study concluded that red dates have antioxidant potential by lowering LDL-cholesterol in human plasma. But this effect is not comparable with hypolipidemic effects of Vitamin E as it also increases good cholesterol i.e. HDL-cholesterol.
Authors and Affiliations
Dr. Shah Murad Mastoi
Keywords
Related Articles
- EP ID EP651136
- DOI -
- Views 100
- Downloads 0
A CROSS-SECTIONAL STUDY ON BENZODIAZIPINE (BZD) ABUSERS OF DHAKA CITY: A SOCIO-PSYCHOLOGICAL CONDITION OF BANGLADESH
Benzodiazepines (BZD) are highly potential drug for abuse among the most frequently prescribed medicine. Different studies say that young-adults are the vulnerable population of BZD misuse in Bangladesh. The aim of the s...
BUCCAL DRUG DELIVERY SYSTEM: A TOOL FOR THE EFFECTIVE DELIVERY OF PHARMACEUTICALS
The Buccal drug delivery system includes drug administration through the buccal mucosa, mainly composed of the lining of the cheeks. Buccal drug delivery system provides a convenient route of administration for both syst...
ROLE OF NON STEROIDAL ANTI-INFLAMMATORY DRUGS IN ACUTE UPPER GASTROINTESTINAL BLEEDING
Many patients presented to the causality with upper gastrointestinal bleeding, which is a serious condition associated with significant morbidity and mortality especially in elderly patients and those with coexisting med...
DETERMINING THE IMPACT RATE OF TRIAGE TRAINING ON AWARENESS AND SKILL LEVEL OF PRE-HOSPITAL EMERGENCY PERSONNEL OF FASA CITY
This study was conducted with the aim of determining the impact of triage training on awareness and skill level of pre-hospital emergency personnel of Fasa City. The present study is applied in respect of objective. The...
FORMULATION AND EVALUATION OF IBUPROFEN GASTRO-RETENTIVE FLOATING TABLETS
The objective of the present study was to formulate the gastro-retentive floating tablets containing Ibuprofen, which would remain in stomach and/or upper part of GIT for prolonged period of time. Floating systems have l...