Comparative Evaluation Of Anticancer Potential Of Moringaoleifera , Ganodermalucidumand Silver Nanoparticles Against B reast And Liver Cancer Cell Lines And Related Pro And Anti Apoptotic Genes Profile
Journal Title: International Journal of Scientific Research and Management - Year 2017, Vol 5, Issue 3
Abstract
The present work aimed to evaluate the anticancer potentials concerning the cytotoxicity and anti - proliferative activity of L - amino acid Oxidase (LAAO) ,MoringaOleifera(MO) Methanol (MLM) and water extracts (MLW), Ganodermalucidum(GL), extracts as a natural products and Silver nanoparticles (AgNP) as well. Cytotoxic effect of test extracts on both breast (MCF - 7) an d liver(HEPG - 2) cancer cell lines varied according to test materials and could be arranged in the order of LAAO > MLM>AgNP> GL>MLW. Also, (MCF7) cell line was more sensitive to test materials compared with (HEPG2) cell line. Regarding the genotoxicity it was found that Bcl2 and survivineand caspase - 3 as antiapoptotic genes were significantly down regulated and P53 as proapoptotic genes was significantly up regulated in both cell lines
Authors and Affiliations
Aliaa Hussein
Keywords
Related Articles
- EP ID EP312836
- DOI -
- Views 99
- Downloads 0
An Examination of the Effect of Migrant Remittances on Human Capital Development & Agricultural Productivity in Nigeria : An ARDL Approach
Thi s study is an attempt to bridge the academic and policy debates on the migration - development nexus using econometric tools of analysis in measuring the impact of migrant inflows or workers‟ remittances on human cap...
Survey on Storage Insect Pest, Methods of Storage and Management Measures on Sorghum Grain around Sub Zoba Hamelmalo , Eritrea
Survey was intended to study the storage insect pests in sorghum around the sub - z oba Hamelmalo. Though this crop is one of the most stable field crops in Eritrea, it is severely infested by many storage insect pests....
Customer Attitudes towards A Public Sector Telecom Company (Bsnl) In Land Line
Customer attitudes are a composite of the three elements: cognitive information, affective information and information concerning a consumer’s past behavior and future inten tions. In other words...
Impact of S scheduled Wastes on Growth: An Input - output Approach
Environmental of good quality is essential for maintaining human life and protecting natural ecosystems. As the economic development contributes in enhancing standard of living, modern lifestyles on the other hand lead t...
Drinking Water Supply Control and Water Theft Identification System
The fast growing of the broad urban residential areas imposes the expansion as well as the sophistication of the present water supply facilities. Along with this one more problems is recognized in the...