Comparative Evaluation of Elisa and Rapid Screening Techniques for the Diagnosis of HCV amongst Suspected Viral Hepatitis Cases Attending Tertiary Care Hospital, Kolkata
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2019, Vol 18, Issue 2
Abstract
HCV is a blood borne virus that attacks the liver and can cause chronic hepatitis, liver cirrhosis (27%) and liver cancer (25%). So detection of HCV infection in suspected patients by a reliable rapid method is a need of hours. The present study was conducted to assess comparative efficacy ELISA and rapid screening techniques (ICT) for the diagnosis of HCV amongst suspected viral hepatitis cases. A total of 2512 nonrepetitive blood samples from patients of various indoor and OPD department were screened for anti-HCV antibody by both ICT and ELISA taking ELISA as a gold standard. The overall prevalence of HCV was found to be .95%. The overall sensitivity and specificity rate of ICT based test was 85.7% and 100% respectively. In comparison ELISA methodology showed both 100% sensitivity and specificity. Although EIAs shows better degree of sensitivity but due to its cost and as it is a time taking procedure it mayless preferable in comparison to ICT in our resourse limited country with high volume of case load.
Authors and Affiliations
Dr Kalidas Ri, Prof (Dr) Raja Ray, Indraneel Roy
Keywords
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- EP ID EP465339
- DOI 10.9790/0853-1802044547.
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