Comparative mydriatic efficacy between mixture containing 0.8% tropicamide 5% phenylephrine and 0.4% and tropicamide 2.5% phenylephrine: A prospective analytical study
Journal Title: Indian Journal of Clinical and Experimental Ophthalmology - Year 2016, Vol 2, Issue 2
Abstract
Background: This study is conducted to know the efficacy of mydriasis of diluted commercially available combination drop of tropicamide and phenylephrine. The pupillary dilation achieved with 0.8% tropicamide and 5% phenylephrine is compared with that of 0.4% tropicamide and 2.5% phenylephrine. Methods: In this prospective analytical study conducted in 100 patients, one eye of each patient was dilated with combination drop of 0.8% and 5% phenylephrine and the other eye was dilated with a diluted concentration of the same eye drops. The drops were instilled at an interval of 10 minutes for 3 times. Mydriasis was recorded at 10, 20, 30, 40 and 60 minutes and difference between the two eyes was observed. Results: The combination of 0.4% Tropicamide and 2.5% phenylephrine has produced an adequate mydriasis (8mm) at 30 and 40 minutes interval with a statistically significant p value of 0.045 and 0.042 respectively. The proportion of patients who required an additional application of drops after 60 minutes interval was statistically insignificant (p= 0.498). The progression of the pupil dilation at 20, 30and 40 minutes was found to be statistically significant with p values of 0.020, 0.003 and 0.022 respectively. A statistically significant difference was found in the dilation between the diabetic group and non-diabetic group at 40 and 60 minutes (p<0.001). Conclusion: The diluted mixture was effective enough to produce an adequate mydriasis for intraocular examination. During the process of attaining an adequate mydriasis it also showed a significant progression in the pupillary dilation. The use of this mixture would possibly reduce the occasional adverse effects of the combination drops of higher concentrations especially in patients with co-morbid systemic conditions.
Authors and Affiliations
Sandhya R, Satya Swapnika
Keywords
Related Articles
- EP ID EP240942
- DOI -
- Views 73
- Downloads 0
Progression of diabetic retinopathy after cataract extraction with intraocular lens implantation
Aim of the study is to observe the progression of diabetic retinopathy in patients after cataract extraction and placement of intraocular lens implantation Diabetes affects both the anterior as well as the posterior segm...
Bandage contact lens: A clinical study
Purpose: To evaluate the efficacy and safety of bandage contact lens in various corneal disorders. Methods: Bandage contact lens was applied to patients who required corneal re-epithelialization promotion or pain reducti...
Cross sectional survey analysis of eye donation awareness among medical, dental and nursing students in a teaching hospital/tertiary hospital
Introduction Visual rehabilitation by corneal transplantation remains the only treatment modality for treatable corneal blindness Unfortunately the demand of the donated cornea remains high in comparison to its procureme...
Prevalence of visual disability due to refractive errors in patients with cerebral palsy
Cerebral palsy a diagnostic term to describe a group of motor disorders of early brain development.(1,2) Children with cerebral palsy should be treated and rehabilitated so that they can live in an inclusive society wher...
Managing delayed onset postoperative Pseudomonas aeruginosa endophthalmitis
Abstract A 58 year old female patient presented with diminution of vision in left eye a week after uneventful manual small incision cataract surgery. Examination showed ciliary congestion, hypopyon and exudative papillar...