Comparative study between intralesional MMR and intralesional BCG in treatment of verruca vulgaris
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 17, Issue 2
Abstract
Background: Cutaneous warts are common dermatological conditions caused by the human papilloma virus (HPV). Immunotherapy has now found a significant place in the treatment of warts because of its non-destructive action, ease of use, and promising results. Objectives:To compare efficacy between intalesional MMR and BCG in treatment of verruca vulgaris. Method: 30 Patients were included in study and divided into two groups. Group1:This group included 15 patients subjected to intralesional MMR. Group 2:This group included 15 patients subjected to intralesional BCG. Only single wart was injected at 2-weeks interval until complete clearance or for a maximum of 5 treatments. Follow up of patients was done every month for 3 months for clinical assessment of results and to show any recurrence. Results: In group1: 73.3% of patients showed complete lesional clearance and 46.6% showed distant lesional clearance . 6% showed erythema around lesion & 26.6% showed hyperpigmentation. In group 2:33.3% showed lesional clearance and 13.3% showed distant lesional clearance. 60% of patients showed lesional ulceration and 30% showed flu like symptom & 53.3% showed hyperpigmentation. There is statistically significant differance (p<0.05) between both groups where MMR showed higher efficacy than BCG. Conclusion:. We found that the treatment of common warts by intralesional MMR vaccine is effective, with good cure rates, and excellent safety profile compared to intralesional BCG.
Authors and Affiliations
Dr. Pooja. Munnangi, Dr. J. Ch. K. L. P. Kishore, Dr. V. Nivedita Devi
Keywords
Related Articles
- EP ID EP362432
- DOI 10.9790/0853-1702074450
- Views 71
- Downloads 0
Perceived Causes Of Infertility And Its Psychosocial Effects Among Women With Infertility Attending Gynecology Clinic In Usmanu Danfodiyo University Teaching Hospital, Sokoto
Background: The desire to have a child is virtually universal, and the right to reproduce is recognised by international conferences as basic human right. Woman with infertility is often looked down upon. These study att...
Study of Gross Motor Functions in Cerebral Palsy Patients
Introduction: The term Cerebral Palsy (CP) was originally coined more than a century ago and loosely translates as “brain paralysis”. Cerebral Palsy is the leading cause of childhood disability affecting function and dev...
Variations In Ada Levels In Various Body Fluids- An Original Study
Aim: The aim of our study was to determine the frequency of various types of basal cell carcinomas encountered in our practice, to delineate the spectrum in our setup and to determine the different histological patterns,...
A Review on Zirconia As The Upcoming Material for Dental Implants
Titanium has been serving as satisfactory material for manufacturing of dental implants. Titanium dental implants have disadvantages like corrosion, radiating ions to the human body as well as having many separate parts...
Dermatoglyphics in Patients of Schizophrenia in Kashmiri Population. A Comparative Study
Background: It is believed that the combination of genetic and environmental factors plays important role in development of schizophrenia. Many structures of the body like the brain, lips, alveoli, etc. develop during th...