Comparative Study of Epidural Ropivacaine versus Ropivacaine Clonidine
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2018, Vol 6, Issue 6
Abstract
Abstract: This is a prospective randomised study conducted at yashoda hospital with the aims to determine the qualitative and quantitative aspects of epidural block, hemodynamic effects, and postoperative pain relief of ropivacaine 0.75% versus ropivacaine 0.75% with 75mcg clonidine in lower limb orthopaedic surgeriesThis study was conducted in 60 patients belonging to ASA grade I and II, scheduled to undergo lower limb orthopaedic surgery (total knee replacement). After random allocation into two different groups R and RC, 30 patients in each group, patients in group RC received 20ml of 0.75% ropivacaine and 75 μg of clonidine. Group R patients were administered 20ml solution of 0.75% ropivacaine. Surgical procedures were initiated after the establishment of adequate surgical anaesthetic effect with minimum level up to T10 dermatome.The onset, time to reach peak sensory and motor level, duration of Analgesia and Motor block, hemodynamic changes, and side effects were recorded. Statistical analysis was done using T-test and ANOVA. P value of less than 0.05 was considered to be significant. The onset of sensory blockade was earlier in Group RC , which was statistically significant (P<0.05), Once sensory level was established at T8 - T10 level, there was no noticeable difference in sensory anaesthesia in two groups throughout the surgical procedure. The onset of motor blockade was earlier in Group RC but statistically not significant (P>0.05) , but the establishment of complete motor blockade was earlier in the RC group which was statistically significant, when compared to Group R (P<0.05).The hypotension was treated with incremental doses of mephenteramine 3 – 6 mg bolus doses. The requirement was more in Group RC but statistically not significant.
Authors and Affiliations
Dr. Nanda Kumar Murari, Dr. Anusha K
Keywords
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