Comparative study of olanzapine and risperidone in the control of positive and negative symptoms in the treatment of schizophrenia
Journal Title: International Journal of Pharmaceutical Chemistry and Analysis - Year 2018, Vol 5, Issue 1
Abstract
Objective To compare the efficacy of olanzapine and risperidone in the treatment of positive and negative symptoms of schizophreniaMaterials and Methods The study was conducted in MGM medical college Navi Mumbai between October 2012 to September 2014 The study included 110 patients of schizophrenia The positive and negative symptoms were assessed with the help of the PANSS positive amp negative symptom score scaleResults We observed that the mean percentage reduction in score in the positive scale of PANSS was 4874 in the risperidone and 4940 in the olanzapine group The negative score reduced by 5632 in the Risperidone group and by 6159 in the olanzapine group on the PANSSConclusion olanzapine was superior to risperidone in controlling the positive as well as negative symptoms of schizophrenia clinically but the results were not statistically significantKeywords Olanzaine Risperidone Schizophrenianbsp
Authors and Affiliations
Supriya Sharma, Yeshwant Deshmukh, Priya Ann Sam, Urmila Salve
Keywords
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- EP ID EP481420
- DOI 10.18231/2394-2797.2018.0002
- Views 92
- Downloads 0
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