Comparative Study of Oral Nifedipine and Intravenous Labetalol for Control of Blood Pressure in Severe Preeclampsia

Abstract

Background-Hypertensive disorders complicates 5-10 % of all pregnancies and is the third common cause of maternal mortality and morbidity next to haemorrhage and infections. Methods- This longitudinal interventional study was conducted in the department of Obstetrics and Gynaecology, P.B.M and Associated Group of Hospitals, attached to Sardar Patel Medical College, Bikaner from February 2017 to January 2018. Results- The mean age of women in Group A was 24.16±4.40 while in Group B it was 24.60±4.92. Both drugs were approximately similar efficacious in reduction of blood pressure. Mean time duration to achieve desired blood pressure was less in group B than in group A and it was statistically significant. The significant difference was observed between mean doses given in both groups to control blood pressure. Conclusion- The choice of antihypertensive agent in severe hypertension in pregnancy should depend on the clinician's experience, familiarity, drug availability and cost of the drugs. This study has shown that both Nifedipine and Labetalol fulfill the criteria required for an antihypertensive drug to treat severe hypertension in pregnancy with adequate efficacy and safety. Both the drugs are equally effective for the same.

Authors and Affiliations

Dr. Santosh Khajotia

Keywords

Related Articles

Comparative Evaluation of Serum Ceruloplasmin Levels in Chronic Periodontitis Patients with and Without Diabetes Before and After Non-Surgical Periodontal Therapy

Introduction: Periodontitis is a common local inflammatory disease of tooth supporting tissues initiated by microorganisms present in dental plaque. Ceruloplasmin is 122 K-D multi copper binding plasma protein helps in...

Pseudo Winging of Scapula Due To Sub Scapular Osteochondroma-A Case Report

Osteochondroma or exostosis is most common primary benign bone tumor and comprising of more than one third of primary bone tumor. Osteochondroma originate mainly from the metaphysis of long bone with more than 35% of cas...

Cultural Factors and Decision Making Process on the Choice and Uptake of Contraceptive Among Women in Sokoto state, Nigeria

Culture as a way of life has impact on verities of women`s lives and determines the decision making process and health seeking behavior. This study describes the cultural factors affecting the uptake of contraceptives a...

Milligan-Morgan Haemorrhoidectomy Versus Stapled Haemorrhoidopexy: A Prospective Comparative Study.

Background: Haemorrhoids being a common anorectal problem, characterized by bleeding from anal canal is known for it’s morbidity and complications. The treatment option depends on the type and severity of the symptoms, o...

Evaluation of Central Nervous System Tumors by Squash and Imprint Cytology with Histopathological Correlation

Introduction: Intraoperative diagnosis of space occupying lesions of the central nervous system is of utmost importance in order to plan the early treatment of patients. The study was designed to find correlation of impr...

Download PDF file
  • EP ID EP501478
  • DOI -
  • Views 131
  • Downloads 0

How To Cite

Dr. Santosh Khajotia (2018). Comparative Study of Oral Nifedipine and Intravenous Labetalol for Control of Blood Pressure in Severe Preeclampsia. International Journal of Medical Science and Innovative Research (IJMSIR), 3(3), 127-131. https://www.europub.co.uk/articles/-A-501478