Comparative Study of Prothrombin Time, Activated Partial Thromboplastin Time and Platelet Counts in Type II Diabetes Mellitus and Healthy Individual
Journal Title: Indian Journal of Pathology: Research and Practice - Year 2019, Vol 8, Issue 4
Abstract
Background: In diabetic patients incidence of cardiovascular disease due to thrombosis is higher than healthy individual. PT, aPTT and Platelet count are haematological parameters that give an idea about the coagulation status. So, this study aimed to assess the prothrombin time, activated partial thromboplastin time and platelet counts of type II diabetes mellitus patients. Methods: A comparative study was conducted at SMIMER hospital, Surat. A total 50 type II diabetic patients and 50 healthy control were included in this study. 4 ml of blood was collected in citrate bulb to determined PT, aPTT and Platelet count of these 2 Groups. Results: The mean aPTT of diabetic and healthy control 25.14 ± 6.32 and 35 ± 3.23 s, respectively. The proportion of diabetic patients with normal PT, aPTTand platelet counts was 84.0%, 10% and 92.0%, respectively. There was significant shortening of aPTT in Type II diabetic patients. Conclusions: There was a significant shortening of aPTT in diabetic patients as compared with non-diabetic groups. So, shortening of aPTT in untreated Type II diabetic patients might be useful marker in patients with diabetes and monitoring of the aPTT in newly diagnosed diabetic patients is important to prevent hypercoagulation.
Authors and Affiliations
Hemaxi Patel
Keywords
Related Articles
- EP ID EP670682
- DOI 10.21088/ijprp.2278.14810.8519.26
- Views 68
- Downloads 0
Holotranscobalamin : A Newer Parameter in Diagnosis of Vitamin B12 Deficiency States
Background and objectives: Vitamin B12 is an essential nutrient that plays crucial roles in the human body. B12 deficiency primarily affects the hematopoietic system, but its effects extend to other tissues and organs, m...
Threats of Transfusion Transmitted Infections: Trends and Seroprevalence among Healthy Blood Donors in Govt. RBM District Hospital Blood Bank: Bharatpur, Rajasthan, India
Background: Transfusion-transmissible infections such as hepatitis B virus (HBV), human immunodeficiency virus (HIV), hepatitis C virus (HCV) and syphilis are among the greatest threats to blood safety for transfusion re...
A Detailed Study of Histomorphological Spectrum of Psoriasiform Dermatitis
Background: Psoriasiform term implies that a lesion clinically or histologically mimics psoriasis. Psoriasiform dermatoses often poses diagnostic dilemma to both pathologists and dermatologists. It is essential to follow...
Study of Diagnostic Efficacy of the Fine Needle Aspiration Cytology of Lymphadenopathy as Compared to Open Biopsy for Histopathological Examination
Background: Lymphadenopathy is an abnormal increase in size and/ or altered consistency of lymph nodes. It is a very common clinical manifestation of regional or systemic disease caused by the invasion or propagation of...
A Study of Histopathological Correlation with Diagnostic Finding of Cytological Smear Evaluated Within the Criteria of TBS
The cervical Pap smear is one of the most successful screening tests utilized in medicine. Since its introduction in the 1950s, the cervical cancer rate in the United States has fallen dramatically. While cervical cancer...