COMPARATIVE STUDY OF THE LUNG VOLUME INCLUDED IN THE TANGENTIAL FIELD IN BODY CONTOUR BASED AND CT SCAN BASED 2-DIMENSIONAL RADIATION PLANNING IN BREAST CANCER TREATMENT
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 21
Abstract
BACKGROUND Pneumonitis and lung fibrosis are some of the major toxicities of radiation in carcinoma breast, and the volume of lung included in radiation field should be as less as possible. One of the limitations of body contour based 2D (2-dimensional) planning is that we cannot assess the volume of lung included in the radiation field. Aims and Objectives- To compare the volume of lung included in the tangential radiation field in body contour-based radiation planning with CT scan based 2-dimensional radiation planning in the radiation treatment of carcinoma breast. MATERIALS AND METHODS Post modified radical mastectomy female patients were selected. For radiation planning, we followed 2D planning method by plotting body contour. A single CT scan slice at the level of centre of tangential fields was also taken. Using the treatment planning system, Greatest Perpendicular Distance (GPD) was measured. The percentage lung volume and absolute lung volume were calculated. The observed data were analysed using SPSS software. A p-value of < 0.05 was considered as significant. RESULTS It was found that the percentage lung volume and the absolute lung volume in CT based planning was less than that in contourbased planning with a difference of median 2.8332 and 79.7783 respectively. Statistical analysis with Wilcoxon signed rank test showed that this difference was significant (p < 0.0001). CONCLUSION The incidence and severity of pneumonitis increase with increasing volume of lung irradiated. GPD can predict the percentage of lung volume irradiated by tangential fields. We can assess GPD using CT scan based 2D planning. This study showed that the percentage lung volume and the absolute lung volume included in the tangential field were significantly less in CT scan based planning method. So, we can reliably use CT scan based 2D planning to reduce the volume of lung irradiated in the treatment of breast cancer in those centres lacking advanced radiation treatment facilities.
Authors and Affiliations
Sajeev George Pulickal, Sivarama Krishnan, Girish Babu M
Keywords
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- EP ID EP431690
- DOI 10.14260/jemds/2018/585
- Views 71
- Downloads 0
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