Comparative Testing of Antibacterial Activity of Aqueous Extract of Bergenia Ligulata Rhizomes and Ethanolic Extract of Butea Monosperma Flowers for Herbal Gel Formulation
Journal Title: IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) - Year 2017, Vol 12, Issue 1
Abstract
The aim of this research was to formulate a gel comprising of the both extracts of Bergenia ligulata rhizomes and Butea monosperma flowers that would aid in wound healing by exhibiting antibacterial activity at the site of wound infection if any. As per the literature survey conducted it was found that aqueous extract of Bergenia ligulata rhizomes and ethanolic extract of Butea monosperma flowers have good potential of antibacterial activity. Hence this antibacterial activity was studied with the help of agar well-diffusion assay method, against the micro-organisms-S. aureus, MRSA, Pr. vulgaris, and E.coli . Both these extracts were obtained through Soxhlet extraction process and this process was optimized to get maximum yield of extraction. By agar gel well- diffusion assay at the concentration of about 100µg/mL both the extracts exhibited maximum zone of inhibition. This concentration was helpful in deciding the dose for topical gel formulation.
Authors and Affiliations
Purva Malik1, Vidhi Bhatia2
Keywords
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- EP ID EP388211
- DOI 10.9790/3008-1201028994
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