Comparative Testing of Antibacterial Activity of Aqueous Extract of Bergenia Ligulata Rhizomes and Ethanolic Extract of Butea Monosperma Flowers for Herbal Gel Formulation
Journal Title: IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) - Year 2017, Vol 12, Issue 1
Abstract
The aim of this research was to formulate a gel comprising of the both extracts of Bergenia ligulata rhizomes and Butea monosperma flowers that would aid in wound healing by exhibiting antibacterial activity at the site of wound infection if any. As per the literature survey conducted it was found that aqueous extract of Bergenia ligulata rhizomes and ethanolic extract of Butea monosperma flowers have good potential of antibacterial activity. Hence this antibacterial activity was studied with the help of agar well-diffusion assay method, against the micro-organisms-S. aureus, MRSA, Pr. vulgaris, and E.coli . Both these extracts were obtained through Soxhlet extraction process and this process was optimized to get maximum yield of extraction. By agar gel well- diffusion assay at the concentration of about 100µg/mL both the extracts exhibited maximum zone of inhibition. This concentration was helpful in deciding the dose for topical gel formulation.
Authors and Affiliations
Purva Malik1, Vidhi Bhatia2
Keywords
Related Articles
- EP ID EP388211
- DOI 10.9790/3008-1201028994
- Views 75
- Downloads 0
Development andValidation of a New, Simple-HPLC Method for Simultaneous Determination ofSofosbuvir, Daclatasvir and Ribavirin in Tablet Dosage Form
A sensitive, simple, selective and accurate HPLC method was developed and validated for Simultaneousanalysis of antiviral drugs,Sofosbuvir, Daclatasvir and Ribavirinthat allowreduction in treatment duration for HCV patie...
Appraisal Of The Utilization Of Contraceptive Devices Among Women Aged 18 – 45yrs In Some Selected Hospitals In Abuja Municipal Area Council Of Federalcapital Territory Abuja
Contraceptives are devices employed to prevent pregnancy. Birth control, also known as contraception and fertility control is a method or device used to prevent pregnancy. The use of birth control and proper Planning is...
Premnocarpon Mohgaoanii Gen. Et. Sp. Nov. A Report of Fossil Drupe Fruit From Deccan Intertrappean Beds of Mohgaonkalan, Dist. Chhindwara, M.P. India
A well preserved drupaceous fruit is collected from Mohgaonkalan, MP, India a well known Deccan Intertrappean Beds fossiliferous locality belonging to uppermost cretaceous period. The present fossil fruit is small, drupa...
Prevalence and Determinants of Malnutrition among Poor Women and Children in the South-West Region of Bangladesh
The objective was to describe the prevalence and determinants of malnutrition and identify the associated factors among the women of ultra poor households targeted by SPRING Bangladesh. SPRING Bangladesh always emphasis...
Transgenic Potato (Solanumtuberosum) Expressing Two Antifungal Thionin Genes Confer Resistance To Fusarium Spp.
Two thionin genes were isolated from Arabidopsis thaliana (AT1G12660 and AT1G12663). The resulted thionin protein has antifungal activity against potato pathogenic fungi like Fusariumsolani and Fusariumoxysporum. These t...