Comparision of Kt/V in Haemodialysis By Daugirdas Method And By Online Clearance Monitoring
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 5
Abstract
Introduction: The measurement of the dialysis dose is a vital element in themanagement of chronic kidney disease patients on maintenance haemodialysis (HD). The dose of haemodialysis is expressed as (K urea x Td)/Vurea (abbreviated as Kt/V).Single-pool variable volume spKt/V is the most widely used at present is the following formulafor calculating Kt/V. Aim: To compare the Kt/V ratio obtained with theDaugirdas formula (D) with the results measured by an Online Clearance Monitor (OCM). Materials and methods: Our study is a cross sectional study of 50 patients on maintenance hemodialysis . Patients dry weight, weight gain between sessions, height, age, sex, blood flow , hematocrit, pre and post blood urea nitrogen were obtained for calculating Kt/V by Daugirdas formula (D). Kt/V results were obtained from the same Fresenius 4008S HD machine equipped with an OCM on the same dialysis session. Results: 50 patients were studied. Out of which 33 were male patients (66%). Mean age of our study patients were 38.74 ± 11.18 years. The duration of hemodialysis didn’t have any statistical significance with Kt/V measured by Kt/V (D) and Kt/V(OCM) by anova test . Independent sample t test showed that delivered Kt/V by brachio cephalic fistula was higher than radio cephalic fistula and p value was 0.01. The Kt/V (D) measured by daugirdas formulae was 1.53 ± 0.22. The Kt/V(OCM) measured by online Clearance Monitor was 1.51 ± 0.21. Intra class correlation co efficient showed a strong agreement between both methods, r = 0.964. Conclusions: In our study, there is good correlation between Kt/V (D) and Kt/V (OCM). Online Clearance Monitor is a practical instrument for daily use, to complement the other formulas, helping to adequate the dialysis dose delivered to reach excellent patient’s benefit.
Authors and Affiliations
S. Sujit, R. Vivek Praveen, J. Jaya Nivash, N. D. Srinivasa Prasad, M. Edwin Fernando
Keywords
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