Comparison of 0.1% Tacrolimus & 0.1% Triamcinolone acetonide in Oral Lichen Planus - A Clinical Study
Journal Title: Journal of Advanced Medical and Dental Sciences Research - Year 2018, Vol 6, Issue 4
Abstract
Background: Lichen planus (LP) is a chronic mucocutaneous disorder that affects oral and genital mucous membranes, skin, nails, and scalp. The present study was conducted to compare 0.1%, triamcinolone acetonide and 0.1% tacrolimus in the management of oral lichen planus. Materials & Methods: The present study comprised of 50 patients of oral lichen planus which was confirmed by clinical examination followed by histopathological examination. They were divided into 2 groups of 25 each. Group I were those who were prescribed 0.1% tacrolimus 4 times daily and group II were put on 0.1% triamcinolone acetonide 4 times daily. Patients were recalled regularly to see improvement in the lesion and were recorded as improved and non- improved. Results: Pain was present in 12 patients in group I and 14 in group II and burning sensation was present in 17 in group I and 19 in group II patients. The difference was non- significant (P> 0.05). Improvement was seen in 18 in group I and 19 in group II and non improvement in 7 in group I and 6 in group II. The difference was non- significant (P> 0.05). Conclusion: OLP is an inflammatory mucosal and cutaneous disorder commonly seen among females. Both 0.1%, triamcinolone acetonide and 0.1% tacrolimus found to be effective in the management of oral lichen planus.
Authors and Affiliations
Adil Rasool Malik, Awadhesh Gupta
Keywords
Related Articles
- EP ID EP544746
- DOI -
- Views 113
- Downloads 0
IMPACT OF PICTORIAL HEALTH WARNING LABELS ON PEOPLE CONSUMING TOBACCO PRODUCTS IN SMOKING FORM
Objective: Tobacco is the main risk factor for cancer and its incidence is increasing day by day. So government authorities are trying attentively to decrease the sale of tobacco products by implementing pictorial warnin...
EPIDERMAL GROWTH FACTOR RESTORES NORMAL LEVELS OF MYOSIN EXPRESSION IN SUBMANDIBULAR SALIVARY GLANDS OF RATS TREATED WITH BOTULINUM TOXIN
Botulinum toxin (BTX) has a number of cosmetic, medical and dental applications. One of the dental applications of BTX is treatment of excessive salivation. Local BTX injection into salivary glands has an effect on the h...
A RARE CASE OF INTRA OSSEOUS SCHWANNOMA IN RETROMOLAR AREA AND REVIEW OF LITERATURE
Schwannomas are one of the benign neoplasms originating from the neural sheath. Soft tissues of the head and neck are the most common sites of occurrence; however, intraosseous schwannomas are rare. Intraoral lesions are...
Assessment of Efficacy of Different Antibiotics in Treating Patients with Ocular Infection
Background:Infection of the eye leads to conjunctivitis, keratitis, endophthalmitis, dacryocystitis, blephritis, infections of eye lid, microbial scleritis, canaliculitis, preseptal cellulitis, orbital cellulitis, endoph...
MANAGEMENT OF MILLER’S CLASS III GINGIVAL RECESSION USING FREE CONNECTIVE TISSUE GRAFTS - THE USE OF TWO DIFFERENT TECHNIQUES
Background: In recent years, dentistry not only demands functional restoration of teeth but also esthetic rehabilitation. A very common issue faced is the presence of gingival recession, which not only is unesthetic but...