Comparison of cellular changes in pituitary gland between the different age groups: A histology-based study

Journal Title: Medpulse International Journal of Anatomy - Year 2019, Vol 9, Issue 1

Abstract

Background: Cells in different parts of pituitary gland (PTG) undergo significant changes according to the age. This study was conducted to evaluate the cellular changes in PTG in relation to age with the use of histology observations. Materials and Methods: The present study was conducted in Department of Anatomy, A total of 73 PTG specimens were collected from foetus and cadavers. Selected specimens were divided into six groups based on the age [(G-I (Less than 1 Y), G-II (1-10 Y), G-III (11-30 Y), G-IV (31-50 Y), G-V (51-70 Y) and G-VI (Above 71 Y)]. All specimens were subjected to Hand E stain. The histology photos were taken under 40X. The slides were observed for cellular changes in PTG. Results: Group-I did not show any cord like arrangement in the periphery and follicular arrangement in the interior. In group-II pars anterior showed cord like arrangement in periphery and follicular arrangement in the interior. Significant changes was observed in the group-III, IV, V and VI compared to other groups regarding cord and follicular arrangement in the peripheral and interior of PTG. There are also significant changes in collagen, acidophils, basophils and cubodial cells in the high age group compared to low age groups. Conclusion: There will be significant changes in cellular appearance and its content as age progress. These changes are important in develop hyper and hypo conditions of PTG. Knowledge about histological changes in PTG improves the treatment strategy inpatients suffering from PTG disorders

Authors and Affiliations

Geetha Jayachandran

Keywords

Related Articles

The morphometric study of the jugular foramen in human adult skulls of Western Maharashtra

Aims and objectives: To study and compare the anthropometric measurements of jugular foramina in human adult skulls of Western Maharashtra. Material and methods: This study was carried out on 100 dry skulls with 65 male...

Unilateral variant origin of first lumbrical

lumbricals, the wing tendons are the intrinsic muscles of hand. They perform flexion at metacarpophalangial joint and extension at interphalangial joint. During routine dissection of an adult male cadaver, we observed un...

Anthropometric study of adult human external ear

Aims and Objectives: To study and compare the normal anthropometric measurements of external ear in males and females of 18-21yrs on either sides. Material and Methods: This study was carried out on 100 medical students...

Molecular or clinical diagnosis of RTT syndrome?

Objectives: Children with delayed developmental milestones and behavioral abnormalities are generally misdiagnosed. So we aim to develop molecular diagnosis of RTT. Method: Karyotyping of the cases has been carried out....

Incidence of accessory head of flexor pollicis longus (Gantzer’s) muscle

Background: The additional head of the flexor pollicis longus muscle is also known as the Gantzer’s muscle. The present study was designed to evaluate the Accessory Head of the Flexor Pollicis Longus muscle and its incid...

Download PDF file
  • EP ID EP487708
  • DOI 10.26611/1001913
  • Views 182
  • Downloads 0

How To Cite

Geetha Jayachandran (2019). Comparison of cellular changes in pituitary gland between the different age groups: A histology-based study. Medpulse International Journal of Anatomy, 9(1), 9-12. https://www.europub.co.uk/articles/-A-487708