Comparison of cellular changes in pituitary gland between the different age groups: A histology-based study
Journal Title: Medpulse International Journal of Anatomy - Year 2019, Vol 9, Issue 1
Abstract
Background: Cells in different parts of pituitary gland (PTG) undergo significant changes according to the age. This study was conducted to evaluate the cellular changes in PTG in relation to age with the use of histology observations. Materials and Methods: The present study was conducted in Department of Anatomy, A total of 73 PTG specimens were collected from foetus and cadavers. Selected specimens were divided into six groups based on the age [(G-I (Less than 1 Y), G-II (1-10 Y), G-III (11-30 Y), G-IV (31-50 Y), G-V (51-70 Y) and G-VI (Above 71 Y)]. All specimens were subjected to Hand E stain. The histology photos were taken under 40X. The slides were observed for cellular changes in PTG. Results: Group-I did not show any cord like arrangement in the periphery and follicular arrangement in the interior. In group-II pars anterior showed cord like arrangement in periphery and follicular arrangement in the interior. Significant changes was observed in the group-III, IV, V and VI compared to other groups regarding cord and follicular arrangement in the peripheral and interior of PTG. There are also significant changes in collagen, acidophils, basophils and cubodial cells in the high age group compared to low age groups. Conclusion: There will be significant changes in cellular appearance and its content as age progress. These changes are important in develop hyper and hypo conditions of PTG. Knowledge about histological changes in PTG improves the treatment strategy inpatients suffering from PTG disorders
Authors and Affiliations
Geetha Jayachandran
Keywords
Related Articles
- EP ID EP487708
- DOI 10.26611/1001913
- Views 180
- Downloads 0
Stature estimation from middle finger length in north Karnataka population, India
Background: Aim of the present study is to establish correlation between stature and middle finger length of both the hands in both males and females separately. Materials and Methods: In the present study, an attempt is...
Anthropometric study of adult human external ear
Aims and Objectives: To study and compare the normal anthropometric measurements of external ear in males and females of 18-21yrs on either sides. Material and Methods: This study was carried out on 100 medical students...
An anatomical evaluation of variations in the terminal branching pattern of facial nerve
Background: Facial nerve is the seventh cranial nerve which supplies all the muscles of facial expressions by its five terminal branches –temporal, zygomatic, buccal, marginal mandibular and cervical. In surgeries like r...
A cadaveric study on Musculocutaneous nerve and its variations in south Indian population
Musculocutaneous Nerve is a branch of the lateral cord of Brachial plexus. It pierces the Coracobrachialis muscle and runs downward between Biceps brachii and Brachialis. At the lateral side of the arm, just below the el...
Coronary dominance pattern among the population of coastal Karnataka: A cadaveric study
Background:The anatomy of coronary arteries is of great clinical importance and any variation is significant for proper interpretation of coronary angiogaraphies and for further surgical repair. The term ‘coronary domina...