Comparison of dexmedetomidine versus midazolam for monitored anesthesia care in patients undergoing vitreoretinal surgery
Journal Title: Eye Science (Yanke Xuebao) - Year 2022, Vol 37, Issue 9
Abstract
[Objective:] The aim of this study was to compare the efficacy and safety of dexmedetomidine versus midazolam for the monitored anesthesia care (MAC) management of patients undergoing vitreoretinal surgery. [Methods:] Forty patients undergoing selective vitreoretinal surgery were double-blind and randomly divided into midazolam group (group M) and dexmedetomidine group (group D), each group had 20 patients. Patients in both groups were anesthetized with posterior bulbous nerve block. Bispectral index (BIS) monitor was connected and the BIS value was maintained between 70 and 90. The mean arterial pressure (MAP), heart rate (HR), respiratory rate (RR), oxygen saturation (SpO2), Ramsay sedation score, numerical rating scale (NRS), surgeon's and patient's anesthesia effect score and adverse reactions were recorded during anesthesia and recovery period. [Results:] Compared with the data of pre-anesthesia, there were statistical differences of the decrease of HR and MAP in group D within the 10 minutes after medication (P<0.05), and the decrease of HR in group D was greater than that in group M (P<0.05). The NRS pain score in group D was significantly lower than that in group M with statistical significance (P<0.001) during the operation and resuscitation, while there was no significant difference in Ramsay sedation score between the two groups during the operation and resuscitation (P>0.05). In terms of adverse reactions to anesthesia, the incidence of spontaneous movement and oxycodone utilization in group D were significantly lower than those in group M (P<0.05). The anesthesia effect scores of surgeons and patients in group D were significantly higher than those in group M (all P<0.001). [Conclusion:] Dexmedetomidine has better analgesic effect and less adverse reactions than midazolam in vitreoretinal surgery.
Authors and Affiliations
Weihong YANG, Weisha LU, Cheng ZHANG, Wenxian LI, Fang TAN
Keywords
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- EP ID EP763739
- DOI 10.3978/j.issn.1000-4432.2022.03.14
- Views 14
- Downloads 0
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